Evidence map›Paper›PMID 26676159›Full record

ArticleCardiovascular diagnosis and therapy2015

Correlation of coronary plaque characteristics and obstructive stenosis with chronic kidney disease by coronary CT angiography.

Chengming Wang, Guanxun Cheng, Yibo Duanmu, Yi Zhu, Lu Xu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chengming Wang1 Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China ; 2 Imaging Department, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Guanxun Cheng1 Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China ; 2 Imaging Department, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Yibo Duanmu1 Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China ; 2 Imaging Department, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Yi Zhu1 Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China ; 2 Imaging Department, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Lu Xu1 Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China ; 2 Imaging Department, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is an independent risk factor for cardiovascular events. We evaluated the correlation of coronary plaque characteristics and obstructive stenosis with CKD by coronary computed tomographic angiography (CCTA).

methodsWe enrolled 491 subjects who were suspected coronary artery disease (CAD) undergoing CCTA. Estimated glomerular filtration rate (eGFR) was calculated by the modification of diet in renal disease (MDRD) equation. Patients were subdivided into four groups based on their eGFR: normal GFR (n=213, eGFR ≥90 mL/min/1.73 m(2)), mild renal insufficiency (n=191, eGFR 60-89 mL/min/1.73 m(2)), moderate renal insufficiency(n=78, eGFR <60 mL/min/1.73 m(2), ≥30 mL/min/1.73 m(2)), and severe renal insufficiency (n=9, eGFR <30 mL/min/1.73 m(2), ≥15 mL/min/1.73 m(2)).

resultsSpearman correlation regression analysis showed that the prevalence of any plaque, calcified plaque (CP), mixed plaque (MP) were positively correlate with CKD (r=0.173, P<0.001; r=0.127, P=0.005; r=0.171, P<0.001), after adjustment for traditional risk factors the prevalence of any plaque and MP were still positively correlate with CKD (r=0.106, P=002; r=0.178, P<0.001). And the prevalence of any stenosis and severe stenosis were positively correlate with CKD (r=0.13, P<0.001; r=0.149, P<0.001), after adjustment for traditional risk factors were still positively correlate with CKD (r=0.134, P=0.003; r=0.174, P<0.001).

conclusionsCKD is closely related with occurrence of CAD. CKD patients from mild renal insufficiency to severe renal insufficiency are the risk factors for CAD. More serious renal function impairment will indicates higher risk of coronary plaque, MP and obstructive stenosis.

Indexed as

Chronic kidney disease (CKD)coronary artery disease (CAD)coronary computed tomographic angiography (CCTA)

Identifiers

PMID26676159
PMCPMC4666694
OpenAlexW2181014106

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.