Evidence map›Paper›PMID 26676028›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Risk stratification for large artery or chronic coronary artery disease-related ischemic stroke in octogenarians undergoing exercise stress myocardial perfusion imaging: A cohort study.

Athanasios Katsikis, Athanasios Theodorakos, Alexandros Drosatos, Konstantinos Konstantinou, Spyridon Papaioannou, Maria Koutelou

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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Role of myocardial perfusion scintigraphy in octogenarians: Time for reappraisal?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Athanasios KatsikisNuclear Medicine Department, Onassis Cardiac Surgery Center, Kallithea, Greece. tkatsikis@gmail.com.
Athanasios TheodorakosNuclear Medicine Department, Onassis Cardiac Surgery Center, Kallithea, Greece.
Alexandros DrosatosCardiology Department, Attikon University Hospital, Athens, Greece.
Konstantinos KonstantinouCardiology Department, 401 General Military Hospital of Athens, Athens, Greece.
Spyridon PapaioannouNuclear Medicine Department, Onassis Cardiac Surgery Center, Kallithea, Greece.
Maria KoutelouNuclear Medicine Department, Onassis Cardiac Surgery Center, Kallithea, Greece.
Onassis Cardiac Surgery Center · GR401 General Military Hospital of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo test, if in octogenarians, treadmill exercise with myocardial perfusion imaging (exercise-MPI) can risk stratify for large artery or chronic CAD-related ischemic stroke (LACCIS).

methodsExercise-MPI-related data of 237 octogenarians (55% prior MI or revascularization) without previous stroke were registered and prospective follow-up was performed to document LACCIS. LACCIS was defined as acute onset of neurological symptoms with CT/MRI findings of non-lacunar-type infarcts in the absence of atrial fibrillation or intracardiac embolic sources.

resultsAfter 7.3 years, 10 LACCIS were documented. SSS [HR 1.08 (1.02-1.13 95% CIs), SDS [HR 1.1 (1.04-1.16 95% CIs)], and non-sustained VT or transient AV block during exercise [HR 3.9 (1.7-9.0 95% CIs)] were predictors of LACCIS (P < .01 for all). A SSS threshold of 16 had 81% specificity for identification of future LACCIS and risk groups formed according to this cut-off had significantly different LACCIS-free survival (P = .015).

conclusionExercise-MPI in octogenarians can provide risk stratification markers for LACCIS.

Indexed as

Aged, 80 and overCausalityComorbidityCoronary Artery DiseaseExercise TestFemaleGeriatric AssessmentGreeceHumansIncidenceMaleMyocardial Perfusion ImagingPrognosisReproducibility of ResultsRisk FactorsSensitivity and Specificityexercise stress testmyocardial perfusion imagingOctogenariansstroke

Identifiers

PMID26676028
OpenAlexW2299987670

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.