ArticleJournal of clinical and diagnostic research : JCDR2015
Ocular Surface Squamous Neoplasia (OSSN): A Retrospective Study.
Article in Journal of clinical and diagnostic research : JCDR, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
- Interferon alpha-2b versus 5-fluorouracil as primary treatment modalities for ocular surface squamous neoplasia: a study of 116 eyes.International ophthalmology · 2025Article
- Demographics, clinical features and prognosis of patients with primary malignant conjunctival tumors at a tertiary hospital in Japan.Japanese journal of ophthalmology · 2025Observational
- Clinical profile and outcomes of ocular surface squamous neoplasia at the Philippine General Hospital: a retrospective study.International journal of ophthalmology · 2025Article
- Novel automated non-invasive detection of ocular surface squamous neoplasia using artificial intelligence.World journal of methodology · 2024Review
- Clinicopathological Correlates of Ocular Surface Squamous Neoplasia.Ocular oncology and pathology · 2024Article
- Anterior lamellar corneoscleral keratoplasty for the management of corneal thinning following treatment with mitomycin-C and interferon to treat highly suspected ocular surface squamous neoplasia: a case report.Arquivos brasileiros de oftalmologia · 2024Article
- Primary Basal Cell Carcinoma of the Conjunctiva.Cureus · 2022Article
- Ocular surface squamous neoplasia in India: a study of 438 patients.International ophthalmology · 2022Article
- Ocular surface squamous neoplasia with intraocular tumour extension: a study of 23 patients.Eye (London, England) · 2020Article
- Widespread Ocular Surface Squamous Neoplasia Treated with Topical Interferon Alpha-2b.Ocular oncology and pathology · 2018Article
- Characteristics, management, and outcome of squamous carcinoma of the conjunctiva in a single tertiary cancer center in Jordan.International journal of ophthalmology · 2018Article
- Lack of relationship between cigarette smoking and alcohol use with dysplasia grade in ocular surface squamous neoplasia.Clinical ophthalmology (Auckland, N.Z.) · 2018Article
- Clinicodemographic profile and treatment outcome in patients of ocular surface squamous neoplasia.Indian journal of ophthalmology · 2017Observational
- Orbital exenteration in immunodeficiency virus-infected patients.Clinical ophthalmology (Auckland, N.Z.) · 2016Article
- Ocular surface squamous neoplasia in Malaysia: A 5-year review.Taiwan journal of ophthalmologyArticle
- Analysis of ocular surface and quality of life in patients with corneal and conjunctival tumors.Arquivos brasileiros de oftalmologiaArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOcular surface squamous neoplasia (OSSN) is a term used to describe neoplastic epithelial abnormalities of conjunctiva and cornea, ranging from Squamous Dysplasia to Invasive Squamous Cell Carcinoma. In recent times, the incidence of OSSN seems to be on the rise, especially in developing countries like India.
aimTo analyse demographic characteristics and compare the clinical presentation, treatment outcomes, and histopathology features of Ocular Surface Squamous Neoplasia (OSSN).
designRetrospective cross-sectional study. MATERIALS AND
methodsWe analysed 113 cases of OSSN who presented to the out-patient department of Sarojini Devi Eye Hospital, Regional Institute of Ophthalmology over a period of three years from February 2012 to January 2015.
resultsIn patients, who presented with OSSN age ranged from 18 to 78 years, mean age being 45.20 years. Males were predominantly affected accounting for 65.48%. A nodule at the limbus is the commonest presentation. About 23% of the patients tested positive for HIV in whom mean age of presentation was 34 years. Among HIV positive patients 78.26% had SCC.
conclusionIncreased incidence of OSSN was observed in males and people with outdoor occupations. Nodular type of lesion is the commonest variety. HIV positive individuals have an increased incidence of OSSN with invasive characteristics. Hence, ophthalmologists need to be aware of this association and a thorough workup is warranted for all patients presenting with OSSN, especially in the younger age group. Our study Also suggests that OSSN may be the first manifestation of underlying HIV infection.
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