ArticleJournal of cachexia, sarcopenia and muscle2015
Cachexia: a nutritional syndrome?
Article in Journal of cachexia, sarcopenia and muscle, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Differences in peak oxygen uptake in heart failure patients with and without cachexia: A systematic review and meta-analysis.Physiological reports · 2025Pooled it
- Using a generative co-design framework to adapt an exercise intervention as part of a multimodal intervention for patients' receiving haemodialysis with or at risk of renal cachexia.Research involvement and engagement · 2026Article
- Combating chronic kidney disease-associated cachexia: A literature review of recent therapeutic approaches.BMC nephrology · 2025Review
- Clinical Importance of Protein Intake in Hospitalized Elderly Patients With Heart Failure.Circulation reports · 2025Article
- Relationship between BMI and prognosis of chronic heart failure outpatients in Vietnam: a single-center study.Frontiers in nutrition · 2023Article
- Cardiac Cachexia: A Well-Known but Challenging Complication of Heart Failure.Clinical interventions in aging · 2020Review
- The Differential Effect of Excess Aldosterone on Skeletal Muscle Mass by Sex.Frontiers in endocrinology · 2019Article
- Skeletal muscle wasting in chronic heart failure.ESC heart failure · 2018Review
- Time to jump on the bandwagon: the Journal of Cachexia, Sarcopenia and Muscle in 2018.Journal of cachexia, sarcopenia and muscle · 2018Article
- Editorial: Defining Undernutrition (Malnutrition) in Older Persons.The journal of nutrition, health & aging · 2018Article
- The mitochondrial metabolic reprogramming agent trimetazidine as an 'exercise mimetic' in cachectic C26-bearing mice.Journal of cachexia, sarcopenia and muscle · 2017Article
- Muscle wasting and sarcopenia in heart failure and beyond: update 2017.ESC heart failure · 2017Review
- Anorexia of ageing: a key component in the pathogenesis of both sarcopenia and cachexia.Journal of cachexia, sarcopenia and muscle · 2017Article
- Prognostic value of simple frailty and malnutrition screening tools in patients with acute heart failure due to left ventricular systolic dysfunction.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Muscle wasting and cachexia in heart failure: mechanisms and therapies.Nature reviews. Cardiology · 2017Review
- Editorial: Weight Loss is a Major Cause of Frailty.The journal of nutrition, health & aging · 2017Article
- Nutritional status in the elderly: misbeliefs, misconceptions and the real world.Wiener klinische Wochenschrift · 2016Article
- Welcome to the ICD-10 code for sarcopenia.Journal of cachexia, sarcopenia and muscle · 2016Article
- Prevalence and clinical impact of cachexia in chronic illness in Europe, USA, and Japan: facts and numbers update 2016.Journal of cachexia, sarcopenia and muscle · 2016Article
- Nutritional Deficiency in Patients with Heart Failure.Nutrients · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cachexia leads to nutritional deficits including anorexia and loss of fat and muscle mass. In persons with precachexia or early cachexia, for example, old persons with weight loss and chronic obstructive pulmonary disease, there is strong evidence that nutritional support improves outcomes. Limited evidence suggests that this may be true for heart failure and chronic kidney disease. The evidence for nutritional support in refractory cachexia is, not surprisingly, less dramatic. It would appear that early in the cachectic process, nutrition, coupled with exercise, may be an important therapeutic approach.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.