ArticleJournal of clinical and diagnostic research : JCDR2015
Can Erectile Dysfunction in Young Patients Serve as a Surrogate Marker for Coronary Artery Disease?
Article in Journal of clinical and diagnostic research : JCDR, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Heart Rate Variability and Erectile Function in Younger Men: A Pilot Study.Applied psychophysiology and biofeedback · 2021Article
- Detection of Coronary Artery Disease by an Erectile Dysfunction Questionnaire.Cardiology research and practice · 2021Article
- Erectile dysfunction therapy in countries where implant is economically not feasible.Translational andrology and urology · 2017Review
- Erectile dysfunction is associated with subclinical carotid vascular disease in young men lacking widely-known risk factors.Asian journal of andrologyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEarly diagnosis and expeditious management of coronary artery disease (CAD) has a rewarding survival benefit.
aimTo study whether erectile dysfunction (ED) serves as a surrogate marker for CAD in a young patient. SETTINGS AND
designMales (n=207) between ages 20-60 years with ED were evaluated prospectively for risk factors for CAD. MATERIALS AND
methodsBlood Glucose Levels (BGL) fasting and post meal), lipid profile (LP) and 12 lead electrocardiogram (ECG) was done in all of them. International Index of Erectile Function-5 (IEF-5) was used for the evaluation of ED. Those with abnormal parameters were assessed by cardiologists by echocardiography, stress test and if necessary coronary angiography (Non-Invasive or Invasive). STATISTICAL ANALYSIS: All the data were analysed using SPSS. 16 statistical software (SPSS Inc., Chicago, IL, USA). All data are expressed as mean and standard deviation. The Student's t-test was used to compare means between groups, and the chi-square test was used to compare proportions between the groups. P-value <0.05 was considered statistically significant. All confidence intervals (CIs) are two tailed and calculated at the 0.05 level.
resultsOut of 207, 149 patients had at least one abnormal screening parameter. All underwent cardiology consultation and 2D ECHO and Stress test. Thirty six patients underwent coronary angiography. CAD was found in 22 patients. Of these, 19 patients had severe ED. Nine patients were between 20-40 years of age (13.23%). All 9 young patients had deranged LP; severe ED. Six patients were smokers while nobody was hypertensive.
conclusionED serves as a surrogate marker for CAD in young patients (p=0.001). Presence of risk factors and lab abnormalities in young patients with ED warrants a cardiology referral to detect CAD.
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