Evidence map›Paper›PMID 26674594›Full record

ArticleJournal of clinical and diagnostic research : JCDR2015

Clinical Profile and Chemotherapy Response in Children with Hodgkin Lymphoma at a Tertiary Care Centre.

Rachna Seth, Rashmi Ranjan Das, Kirti Puri, Prashant Singh

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rachna SethAdditional Professor, Department of Pediatrics, All India Institute of Medical Sciences (AIIMS) , New Delhi, India .
Rashmi Ranjan DasAssistant Professor, Department of Pediatrics, All India Institute of Medical Sciences (AIIMS) , Bhubaneswar, India .
Kirti PuriIntern, Department of Pediatrics, All India Institute of Medical Sciences (AIIMS) , New Delhi, India .
Prashant SinghIntern, Department of Pediatrics, All India Institute of Medical Sciences (AIIMS) , New Delhi, India .
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOptimal treatment strategy in children with advance stage Hodgkin Lymphoma (HL) still remains controversial.

aimTo evaluate the clinical profile and the efficacy of chemotherapy (CT) as a treatment modality in paediatric HL. MATERIAL AND

methodsRetrospective case record evaluation of paediatric HL cases over 5 years (October 2005 to October 2010) period.

resultsThirty five cases (31 boys) with a median age of eight years were studied. 24 cases were <10-year-old, and 23 had late stage disease (stage III to IV). B-symptoms were present in 60%, bulky mediastinal disease in 25.7%, and spleen involvement in 60% cases. None had bone marrow involvement. Most common histological type was nodular sclerosis (28.6%). Most cases received ABVD/COPP or ABVD regimen. Two cases needed BEACOPP due to progressive disease, and 4 needed low-dose involved field radiotherapy (RT). At a mean (SD) extended event-free follow-up of 42.7(±17.1) months, four cases relapsed (one was lost to follow-up, and three were treated with chemotherapy and low-dose involved field RT). None died due to the disease.

conclusionPresent study found systemic CT alone to be an effective therapy in childhood Hodgkin lymphoma. However, a small sample in present study limits the generalisability of these findings. The findings needs to be replicated in larger population, preferably randomized clinical trials, before any firm conclusion can be made.

Indexed as

Combined Chemo–RadiotherapyNodalPaediatric

Identifiers

PMID26674594
PMCPMC4668499
OpenAlexW2407371736

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.