Evidence map›Paper›PMID 26674475›Full record

ArticleBiomacromolecules2016

Synthesis and Self-Assembly of Bundle-Forming α-Helical Peptide-Dendron Hybrids.

Jeannette E Marine, Shuang Song, Xiaoli Liang, Jonathan G Rudick

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomacromolecules, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeannette E MarineDepartment of Chemistry, Stony Brook University , Stony Brook, New York 11794-3400, United States.
Shuang SongDepartment of Chemistry, Stony Brook University , Stony Brook, New York 11794-3400, United States.
Xiaoli LiangDepartment of Chemistry, Stony Brook University , Stony Brook, New York 11794-3400, United States.
Jonathan G RudickDepartment of Chemistry, Stony Brook University , Stony Brook, New York 11794-3400, United States.

Funding

Acquisition of an Applied Biosystems 4000 QTRAP Mass SpectrometerS10RR023680 · NCRR · STATE UNIVERSITY NEW YORK STONY BROOK · PI IDEN, CHARLES R · 2007 to 2007
$435k
NCRR NIH HHS 1 S10 RR023680-1NCRR NIH HHS S10 RR023680
6 · The paper itself

Abstract

Dendronized helix bundle assemblies combine the sequence diversity and folding properties of proteins with the tailored physical properties of dendrimers. Assembly of peptide-dendron hybrids into α-helical bundles encapsulates the helix bundle motif in a dendritic sheath that will allow the functional, protein-like domain to be transplanted to nonbiological environments. A bioorthogonal graft-to synthetic strategy for preparing helix bundle-forming peptide-dendron hybrids is described herein for hybrids 1a, 1b, and 2. Titration experiments monitored by circular dichroism spectroscopy support our self-assembly model for how the peptide-dendron hybrids self-assemble into α-helical bundles with the dendrons on outside of the bundle.

Indexed as

Protein FoldingAmino Acid SequenceCircular DichroismDendrimersPeptidesProtein Structure, SecondaryProtein Structure, TertiaryDendrimersPeptides

Identifiers

PMID26674475
PMCPMC4710556

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.