ArticleBMC plant biology2015
Metabolomics of dates (Phoenix dactylifera) reveals a highly dynamic ripening process accounting for major variation in fruit composition.
Article in BMC plant biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 52 citations in OpenAlex.
- Comparative Biochemical Profiling of Three Commercial Date Palm Cultivars (Sukkary, Mejhoul, and Khlass) During Fruit Development.International journal of molecular sciences · 2026Article
- Stage-specific nutritional blueprints of date fruit revealed by integrated LC-MS metabolomics and ICP-OES profiling.NPJ science of food · 2026Article
- Genome-wide association of dry (Tamar) date palm fruit color.The plant genome · 2023Article
- Impact of Modified Atmosphere Packaging Conditions on Quality of Dates: Experimental Study and Predictive Analysis Using Artificial Neural Networks.Foods (Basel, Switzerland) · 2023Article
- Decontamination potential of date palm fruit via non-thermal plasma technique.Scientific reports · 2022Article
- Patterns of Volatile Diversity Yield Insights Into the Genetics and Biochemistry of the Date Palm Fruit Volatilome.Frontiers in plant science · 2022Article
- Deletion of beta-fructofuranosidase (invertase) genes is associated with sucrose content in Date Palm fruit.Plant direct · 2020Article
- Unraveling dynamic metabolomes underlying different maturation stages of berries harvested fromJournal of ginseng research · 2020Article
- GC-MS Based Metabolite Profiling to Monitor Ripening-Specific Metabolites in Pineapple (Metabolites · 2020Article
- Polyamines Regulate Strawberry Fruit Ripening by Abscisic Acid, Auxin, and Ethylene.Plant physiology · 2018Article
- Nutrimetabolomics: An Update on Analytical Approaches to Investigate the Role of Plant-Based Foods and Their Bioactive Compounds in Non-Communicable Chronic Diseases.International journal of molecular sciences · 2016Review
- Dates fruits effects on blood glucose among patients with diabetes mellitus: A review and meta-analysis.Pakistan journal of medical sciencesReview
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDates are tropical fruits with appreciable nutritional value. Previous attempts at global metabolic characterization of the date metabolome were constrained by small sample size and limited geographical sampling. In this study, two independent large cohorts of mature dates exhibiting substantial diversity in origin, varieties and fruit processing conditions were measured by metabolomics techniques in order to identify major determinants of the fruit metabolome.
resultsMultivariate analysis revealed a first principal component (PC1) significantly associated with the dates' countries of production. The availability of a smaller dataset featuring immature dates from different development stages served to build a model of the ripening process in dates, which helped reveal a strong ripening signature in PC1. Analysis revealed enrichment in the dry type of dates amongst fruits with early ripening profiles at one end of PC1 as oppose to an overrepresentation of the soft type of dates with late ripening profiles at the other end of PC1. Dry dates are typical to the North African region whilst soft dates are more popular in the Gulf region, which partly explains the observed association between PC1 and geography. Analysis of the loading values, expressing metabolite correlation levels with PC1, revealed enrichment patterns of a comprehensive range of metabolite classes along PC1. Three distinct metabolic phases corresponding to known stages of date ripening were observed: An early phase enriched in regulatory hormones, amines and polyamines, energy production, tannins, sucrose and anti-oxidant activity, a second phase with on-going phenylpropanoid secondary metabolism, gene expression and phospholipid metabolism and a late phase with marked sugar dehydration activity and degradation reactions leading to increased volatile synthesis.
conclusionsThese data indicate the importance of date ripening as a main driver of variation in the date metabolome responsible for their diverse nutritional and economical values. The biochemistry of the ripening process in dates is consistent with other fruits but natural dryness may prevent degenerative senescence in dates following ripening. Based on the finding that mature dates present varying extents of ripening, our survey of the date metabolome essentially revealed snapshots of interchanging metabolic states during ripening empowering an in-depth characterization of underlying biology.
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