Evidence map›Paper›PMID 26673520›Full record

ArticleEthnicity & disease2015

Associations of Abdominal Muscle Area with 4-Year Change in Coronary Artery Calcium Differ by Ethnicity Among Post-Menopausal Women.

Christina L Wassel, Gail A Laughlin, Sarah D Saad, Maria Rosario G Araneta, Wilma Wooten, Elizabeth Barrett-Connor, Matthew A Allison

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ethnicity & disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Christina L Wassel1. Department of Pathology and Laboratory Medicine, College of Medicine, University of Vermont.
Gail A Laughlin2. Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, Calif.
Sarah D Saad3. Division of Preventive Medicine, Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, Calif.
Maria Rosario G Araneta2. Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, Calif.
Wilma Wooten4. County of San Diego, Health and Human Services Agency, Public Health Services.
Elizabeth Barrett-Connor2. Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, Calif.
Matthew A Allison3. Division of Preventive Medicine, Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, Calif.
University of California, San Diego · USHealth and Human Services Agency · USUniversity of Vermont · US

Funding

A Prospective Study of Adiposity and Subclinical Coronary Artery DiseaseR21HL089622 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WASSEL, CHRISTINA L. · 2009 to 2010
$425k
NHLBI NIH HHS R21 HL089622NHLBI NIH HHS R21HL089622
6 · The paper itself

Abstract

objectiveTo examine the association of abdominal muscle area with coronary artery calcium (CAC) presence, extent, and progression in a multi-ethnic cohort of older, community-dwelling post-menopausal women. DESIGN AND

settingCross-sectional and longitudinal population-based cohort.

participantsThe sample comprised 179 non-Hispanic White women, 116 Filipina women and 144 African American women, all without known CVD, who underwent chest and abdominal computed tomography (CT) scans twice about four years apart for abdominal muscle and fat, as well as CAC.

main outcome measuresCAC presence, extent and progression.

resultsThere was a significant interaction of ethnicity with baseline oblique muscle area (p-for-interaction .01), and marginally significant interactions with baseline total and paraspinal muscle for change in CAC (p-for-interactions both .09). Among Filipina women, each standard deviation (SD) greater total muscle area was associated with a 26% (95% CI (-43%, -4%), P=.02) reduced rate of change in CAC; higher paraspinal and oblique muscle area were associated with a 24% (-38%, -6%, P=.01) and a 37% (-53%, -16%, P=.0002) reduced rate of change in CAC, respectively. These associations were not significant in African American or non-Hispanic White women. There were no significant associations of abdominal muscle with CAC presence or extent, nor were there significant ethnicity by muscle interactions in these models.

conclusionsAmong Filipina women, greater abdominal muscle mass is associated with a decreased rate of CAC progression. Higher muscle mass may be important for this group in reducing CVD outcomes.

Indexed as

AsianBlack or African AmericanWhite PeopleAbdominal FatAbdominal MusclesAgedAged, 80 and overAge FactorsCohort StudiesCoronary Artery DiseaseDisease ProgressionFemaleHumansMiddle AgedPhilippinesPostmenopauseAbdominal MuscleCoronary Artery CalciumEthnicityMuscle MassRace

Identifiers

PMID26673520
PMCPMC4671440
OpenAlexW2279550140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.