ArticleScientific reports2015
Metabolomic analysis with GC-MS to reveal potential metabolites and biological pathways involved in Pb &Cd stress response of radish roots.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed, 148 citations in OpenAlex.
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- Plasma treated water with metal ions enhances Pak Choi growth, salinity tolerance and accumulation of primary metabolites.Fundamental research · 2025Article
- Metabolomic evaluation of selenium seed priming on mitigating lead stress toxicity in Vicia faba plants.BMC plant biology · 2025Article
- Leveraging multi-omics tools to comprehend responses and tolerance mechanisms of heavy metals in crop plants.Functional & integrative genomics · 2024Review
- Novel endophytic fungal species Pithoascus kurdistanensis producing morphine compounds.Scientific reports · 2024Article
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- Applications of chromatographic methods in metabolomics: A review.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2024Review
- Influence of Cold Stress on Physiological and Phytochemical Characteristics and Secondary Metabolite Accumulation in Microclones ofInternational journal of molecular sciences · 2024Article
- Combined interactions of amino acids and organic acids in heavy metal binding in plants.Plant signaling & behavior · 2023Article
- Metabolic Adjustment of High Intertidal AlgaInternational journal of molecular sciences · 2023Article
- Comparative metabolomics of root-tips reveals distinct metabolic pathways conferring drought tolerance in contrasting genotypes of rice.BMC genomics · 2023Article
- Short-Term Effects ofPlants (Basel, Switzerland) · 2023Article
- Physiology and metabonomics reveal differences in drought resistance among soybean varieties.Botanical studies · 2022Article
- Metabolite Profiles Provide Insights into Underlying Mechanism inPlants (Basel, Switzerland) · 2022Article
- Metabolites produced by inoculated Vigna radiata during bacterial assisted phytoremediation of Pb, Ni and Cr polluted soil.PloS one · 2022Article
- Cotton straw biochar and compoundFrontiers in plant science · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The radish (Raphanus sativus L.) is an important root vegetable crop. In this study, the metabolite profiling analysis of radish roots exposed to lead (Pb) and cadmium (Cd) stresses has been performed using gas chromatography-mass spectrometry (GC-MS). The score plots of principal component analysis (PCA) and partial least squares-discriminate analysis (PLS-DA) showed clear discrimination between control and Pb- or Cd-treated samples. The metabolic profiling indicated Pb or Cd stress could cause large metabolite alteration mainly on sugars, amino acids and organic acids. Furthermore, an integrated analysis of the effects of Pb or Cd stress was performed on the levels of metabolites and gene transcripts from our previous transcriptome work in radish roots. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of integration data demonstrated that exposure of radish to Pb stress resulted in profound biochemical changes including carbohydrate metabolism, energy metabolism and glutathione metabolism, while the treatment of Cd stress caused significant variations in energy production, amino acid metabolism and oxidative phosphorylation-related pathways. These results would facilitate further dissection of the mechanisms of heavy metal (HM) accumulation/tolerance in plants and the effective management of HM contamination in vegetable crops by genetic manipulation.
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