Evidence map›Paper›PMID 26672127›Full record

Trial reportJournal of feline medicine and surgery2016

Evaluation of meloxicam for the treatment of obstructive feline idiopathic cystitis.

Roswitha Dorsch, Friederike Zellner, Bianka Schulz, Carola Sauter-Louis, Katrin Hartmann

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of feline medicine and surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Article
  4. Article
  5. Article
  6. Article
  7. Effect of intermittent bladder flushing on recurrence rate in feline urethral obstruction: 72 cases.The Canadian veterinary journal = La revue veterinaire canadienne · 2022
    Article
  8. The urinary lipid profile in cats with idiopathic cystitis.The Journal of veterinary medical science · 2022
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. In-hospital medical management of feline urethral obstruction: A review of recent clinical research.The Canadian veterinary journal = La revue veterinaire canadienne · 2020
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Roswitha Dorsch1 Clinic of Small Animal Medicine, LMU University Munich, Munich, Germany.
Friederike Zellner1 Clinic of Small Animal Medicine, LMU University Munich, Munich, Germany.
Bianka Schulz1 Clinic of Small Animal Medicine, LMU University Munich, Munich, Germany.
Carola Sauter-Louis2 Clinic for Ruminants, LMU University Munich, Munich, Germany.
Katrin Hartmann1 Clinic of Small Animal Medicine, LMU University Munich, Munich, Germany.
Ludwig-Maximilians-Universität München · DELMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives The aim of the study was to investigate the effect of the non-steroidal anti-inflammatory drug meloxicam on the clinical course of obstructive idiopathic cystitis in cats in a placebo-controlled clinical study. Methods Thirty-seven cats with obstructive idiopathic cystitis were enrolled. Cats received supportive treatment and an indwelling transurethral catheter for 48 h. On days 0 and 1, all cats received buprenorphine 0.01 mg/kg subcutaneously every 8 h. On day 1, cats were randomly assigned to the meloxicam (n = 18) or placebo group (n = 19) and received meloxicam (0.1 mg/kg on day 1, 0.05 mg/kg on days 2-5) or placebo orally for five consecutive days. Cats were monitored by repeated physical examinations and urinalysis, and with a 5 day questionnaire filled in by the owners after discharge and a telephone interview 3 months after presentation. Parameters for evaluation of treatment success were the occurrence of recurrent urethral obstruction, results of physical examinations and questionnaires. Results Recurrent urethral obstruction occurred in 4/18 cats (22%) in the meloxicam group and 5/19 cats (26%) in the placebo group ( P = 1.000). General demeanour and pain on abdominal palpation during hospitalisation improved significantly in both groups ( P <0.001). After discharge, with regard to general demeanour, food intake and voiding behaviour, there were no significant differences within or between groups at different time points. Conclusions and relevance Orally administered meloxicam for 5 days did not influence the incidence of recurrent urethral obstruction and the recovery from clinical signs in cats with obstructive feline idiopathic cystitis. The persistence of clinical signs in most of the cats 1 week after initial presentation indicates that symptomatic treatment for a longer period of time is warranted.

Indexed as

Administration, OralAnimalsAnti-Inflammatory Agents, Non-SteroidalCat DiseasesCatsCystitisDouble-Blind MethodDrug Administration ScheduleFemaleHumansMaleMeloxicamOwnershipPainPain MeasurementSurveys and QuestionnairesAnti-Inflammatory Agents, Non-SteroidalMeloxicamThiazinesThiazoles

Identifiers

PMID26672127
PMCPMC11132225
OpenAlexW2196899332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.