ArticlePsychological medicine2016
A prospective longitudinal model predicting early adult alcohol problems: evidence for a robust externalizing pathway.
Article in Psychological medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The association between early life mental health and alcohol use behaviours in adulthood: A systematic review.PloS one · 2020Pooled it
- Bridging the gap between genetic epidemiological research and prevention: A randomized control trial of a novel personalized feedback program for alcohol and cannabis use.Drug and alcohol dependence · 2023Trial
- Psychopathy Facets Differentially Predict Drug- and Alcohol-Related Problems Following Violent Injury.Behavioral sciences (Basel, Switzerland) · 2026Article
- Elucidating psychosocial outcome profiles as a function of aggregate genetic risk for suicide attempt and alcohol use disorder.Translational psychiatry · 2026Article
- Delineating trajectories of alcohol consumption and alcohol problems from adolescence to young adulthood: An integrated assessment of genetic, familial, and psychosocial factors.Alcohol, clinical & experimental research · 2025Article
- Are Depressive and Anxiety Symptoms Differentially Associated with Alcohol Use Behaviors: Multivariate Behavioral Genetic Analyses.Behavior genetics · 2025Article
- Polygenic overlap of substance use behaviors and disorders with externalizing and internalizing problems independent of genetic correlations.Psychological medicine · 2025Article
- Developmental trajectories of child and adolescent emotional problems: associations with early adult alcohol use behaviors.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Longitudinal links from attachment with mothers and fathers to adolescent substance use: Internalizing and externalizing pathways.Developmental science · 2024Article
- Negative Affect, Sensation Seeking, and Adolescent Substance Use Development: The Moderating Role of Executive Function.Journal of youth and adolescence · 2024Article
- Alcohol milestones and internalizing, externalizing, and executive function: longitudinal and polygenic score associations.Psychological medicine · 2024Article
- Substance use patterns in 9 to 13-year-olds: Longitudinal findings from the Adolescent Brain Cognitive Development (ABCD) study.Drug and alcohol dependence reports · 2022Article
- Multidimensional Quality of Life Across the Spectrum of Alcohol Use Behavior.Psychiatric research and clinical practice · 2022Article
- The externalizing and internalizing pathways to marijuana use initiation: Examining the synergistic effects of impulsiveness and sensation seeking.Developmental psychology · 2021Article
- Early life mental health and problematic drinking in mid-adulthood: evidence from two British birth cohorts.Social psychiatry and psychiatric epidemiology · 2021Article
- Externalizing Risk Pathways for Adolescent Substance Use and Its Developmental Onset: A Canadian Birth Cohort Study: Trajectoires de comportements extériorisés et le risque pour l'initiation et l'usage de substances des adolescents : Une étude de cohorte de naissance canadienne.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2021Article
- Predicting Alcohol Dependence Symptoms by Young Adulthood: A Co-Twin Comparisons Study.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2021Article
- Risk and resilience for alcohol use disorder revealed in brain functional connectivity.NeuroImage. Clinical · 2021Article
- Article
- Applicability of the Theory of Planned Behavior for Predicting Alcohol Use in Spanish Early Adolescents.International journal of environmental research and public health · 2020Article
Corrections and comments
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4 authors.
Funding
Abstract
backgroundRisk factors for alcohol problems (AP) include biological and environmental factors that are relevant across development. The pathways through which these factors are related, and how they lead to AP, are optimally considered in the context of a comprehensive developmental model.
methodUsing data from a prospectively assessed, population-based UK cohort, we constructed a structural equation model that integrated risk factors reflecting individual, family and peer/community-level constructs across childhood, adolescence and young adulthood. These variables were used to predict AP at the age of 20 years.
resultsThe final model explained over 30% of the variance in liability to age 20 years AP. Most prominent in the model was an externalizing pathway to AP, with conduct problems, sensation seeking, AP at age 17.5 years and illicit substance use acting as robust predictors. In conjunction with these individual-level risk factors, familial AP, peer relationships and low parental monitoring also predicted AP. Internalizing problems were less consistently associated with AP. Some risk factors previously identified were not associated with AP in the context of this comprehensive model.
conclusionsThe etiology of young adult AP is complex, influenced by risk factors that manifest across development. The most prominent pathway to AP is via externalizing and related behaviors. These findings underscore the importance of jointly assessing both biologically influenced and environmental risk factors for AP in a developmental context.
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