ArticleJournal of the American College of Cardiology2015
Idiopathic Ventricular Arrhythmias Originating From the Pulmonary Sinus Cusp: Prevalence, Electrocardiographic/Electrophysiological Characteristics, and Catheter Ablation.
Article in Journal of the American College of Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03258112 (Safety and Efficacy of Catheter Ablation of Idiopathic Ventricular Arrhythmias Arising From Cardiac Outflow Tracts), which is not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Efficacy of Catheter Ablation of Idiopathic Ventricular Arrhythmias Arising From Cardiac Outflow Tracts
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias: Executive summary.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2020Pooled it
- 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2020Pooled it
- Electrocardiographic features, mapping and ablation of idiopathic outflow tract ventricular arrhythmias.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2020Pooled it
- Understanding Cardiac Anatomy and Imaging to Improve Safety of Procedures: The Right Ventricular Outflow Tract, Part 1.JACC. Case reports · 2026Article
- Health care utilization for premature ventricular complexes in acute settings.Heart rhythm O2 · 2026Article
- Pulmonary sinus cusp-inclusive mapping and ablation for paediatric right ventricular outflow tract ventricular arrhythmias.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Management of Idiopathic Outflow Tract Ventricular Arrhythmias.Arrhythmia & electrophysiology review · 2026Review
- Cardiac phase variability in pulmonary root geometry: implications for electrophysiological mapping and ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Radiofrequency ablation of a reentrant atrial tachycardia at the superior left atrium via the pulmonary artery.HeartRhythm case reports · 2025Article
- Intracardiac echocardiography-guided discrete potential mapping for arrhythmias from right ventricular outflow tract.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- [Ventricular tachycardia-without structural heart disease: History].Herzschrittmachertherapie & Elektrophysiologie · 2024Review
- [Long-term results of catheter ablation of idiopathic and structural ventricular tachycardia].Herzschrittmachertherapie & Elektrophysiologie · 2023Review
- Electrocardiographic Characteristics, Identification, and Management of Frequent Premature Ventricular Contractions.Diagnostics (Basel, Switzerland) · 2023Review
- Optimal ablation strategy for idiopathic ventricular arrhythmia arising from right ventricular outflow tract: when to perform reversed-U curve technique?Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023Article
- Epicardial catheter ablation of idiopathic ventricular arrhythmias originating from uncommon epicardial sites.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023Article
- Tongmai Yangxin Pill combined with metoprolol or metoprolol alone for the treatment of symptomatic premature ventricular complex: a multicenter, randomized, parallel-controlled clinical study.Journal of geriatric cardiology : JGC · 2022Article
- Electrocardiographic criteria for localization of ventricular premature complexes from the inferior right ventricular outflow tract.Frontiers in cardiovascular medicine · 2022Article
- Pulmonary Artery Isolation for Polymorphic Outflow Tract Ventricular Tachycardia.JACC. Case reports · 2021Article
- Ablation of Ventricular Arrhythmias Arising From the Pulmonary Artery.JACC. Case reports · 2021Article
- Automatic annotation of local activation time was improved in idiopathic right ventricular outflow tract ventricular arrhythmia by novel electrogram "Lumipoint" algorithm.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021Article
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
- Commented on by
- Commented on by
- Commented on by
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdiopathic ventricular arrhythmias (VAs) originating from the pulmonary sinus cusp (PSC) have not been sufficiently clarified.
objectivesThe goal of this study was to investigate the prevalence, electrocardiographic characteristics, mapping, and ablation of idiopathic VAs arising from the PSC.
methodsData were analyzed from 218 patients undergoing successful endocardial ablation of idiopathic VAs with a left bundle branch block morphology and inferior axis deviation.
resultsTwenty-four patients had VAs originating from the PSC. In the first 7 patients, initial ablation performed in the right ventricular outflow tract failed to abolish the clinical VAs but produced a small change in the QRS morphology in 3 patients. In all 24 patients, the earliest activation was eventually identified in the PSC, at which a sharp potential was observed preceding the QRS complex onset by 28.2 ± 2.9 ms. The successful ablation site was in the right cusp (RC) in 10 patients (42%), the left cusp (LC) in 8 (33%), and the anterior cusp (AC) in 6 (25%). Electrocardiographic analysis showed that RC-VAs had significantly larger R-wave amplitude in lead I and a smaller aVL/aVR ratio of Q-wave amplitude compared with AC-VAs and LC-VAs, respectively. The R-wave amplitude in inferior leads was smaller in VAs localized in the RC than in the LC but did not differ between VAs from the AC and LC.
conclusionsVAs arising from the PSC are not uncommon, and RC-VAs have unique electrocardiographic characteristics. These VAs can be successfully ablated within the PSC.
Indexed as
Identifiers
26670064What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.