Evidence map›Paper›PMID 26670010›Full record

ArticleBMC research notes2015

Generic medicines and generic substitution: contrasting perspectives of stakeholders in Ireland.

A O'Leary, C Usher, M Lynch, M Hall, L Hemeryk, S Spillane, P Gallagher, M Barry

Abstract read
In one paragraph

Article in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A O'LearyNational Centre for Pharmacoeconomics, St. James's Hospital, Dublin 8, Ireland. aoleary@stjames.ie.
C UsherNational Centre for Pharmacoeconomics, St. James's Hospital, Dublin 8, Ireland. cusher@stjames.ie.
M LynchSchool of Pharmacy, Royal College of Surgeons, St. Stephens Green, Dublin 2, Ireland. Matthewlynch@rcsi.ie.
M HallDepartment of Pharmacology and Therapeutics, St. James's Hospital, Dublin 8, Ireland. Mhall@stjames.ie.
L HemerykDepartment of Pharmacology and Therapeutics, St. James's Hospital, Dublin 8, Ireland. LHemeryk@stjames.ie.
S SpillaneNational Centre for Pharmacoeconomics, St. James's Hospital, Dublin 8, Ireland. sspillane@stjames.ie.
P GallagherSchool of Pharmacy, Royal College of Surgeons, St. Stephens Green, Dublin 2, Ireland. pgallagher@rcsi.ie.
M BarryNational Centre for Pharmacoeconomics, St. James's Hospital, Dublin 8, Ireland. mbarry@stjames.ie.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Health (Pricing and Supply of Medical Goods) Act 2013 passed into law in July 2013 and legislated for generic substitution in Ireland. The aim of the study was to ascertain the knowledge and perceptions of stakeholders i.e. patients, pharmacists and prescribers, of generic medicines and to generic substitution with the passing of legislation.

methodsThree stakeholder specific questionnaires were developed to assess knowledge of and perceptions to generic medicines and generic substitution. Purposive samples of patients, prescribers and pharmacists were analysed. Descriptive quantitative and qualitative analyses were undertaken. RESULTS AND DISCUSSION: A total of 762 healthcare professionals and 353 patients were recruited. The study highlighted that over 84% of patients were familiar with generic medicines and are supportive of the concept of generic substitution. Approximately 74% of prescribers and 84% of pharmacists were supportive of generic substitution in most cases. The main areas of concern highlighted by the healthcare professionals that might impact on the successful implementation of the policy, were the issue of bioequivalence with generic medicines, the computer software systems used at present in general practitioner (GP) surgeries and the availability of branded generics. The findings from this study identify a high baseline rate of acceptance to generic medicines and generic substitution among patients, prescribers and pharmacists in the Irish setting. The concerns of the main stakeholders provide a valuable insight into the potential difficulties that may arise in its implementation, and the need for on-going reassurance and proactive dissemination of the impact of the generic substitution policy.

conclusionThe existing positive attitude to generic medicines and generic substitution among key stakeholders in Ireland to generic substitution, combined with appropriate support and collaboration should result in the desired increase in rates of prescribing, dispensing and use of generic medicines.

Indexed as

Attitude of Health PersonnelDrugs, GenericDrug SubstitutionFemaleGeneral PractitionersHealth Knowledge, Attitudes, PracticeHumansIrelandMalePatientsPharmacistsSurveys and QuestionnairesDrugs, Generic

Identifiers

PMID26670010
PMCPMC4678461

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.