ArticleWorld journal of surgery2016
Economic Valuation of the Global Burden of Cleft Disease Averted by a Large Cleft Charity.
Article in World journal of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review of the Cost-Effectiveness of Cleft Care in Low- and Middle-Income Countries: What is Needed?The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2023Pooled it
- Impact of short-term reconstructive surgical missions: a systematic review.BMJ global health · 2019Pooled it
- Evolution of Cleft Lip and Palate Surgery and the Pursuit for Consensus on Standardized Algorithms of Care.Plastic and reconstructive surgery. Global open · 2025Article
- Economic Evaluation of a Global Reconstructive Surgery Visiting Educator Program.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022Article
- Cleft Lip and Palate Research in Low- and Middle-income Countries: A Scientometric Analysis.Plastic and reconstructive surgery. Global open · 2022Article
- Current Applications of Artificial Intelligence in Cleft Care: A Scoping Review.Frontiers in medicine · 2021Article
- Developing Metrics to Define Progress in Children's Surgery.World journal of surgery · 2019Review
- Creating Value in Plastic Surgery.Seminars in plastic surgery · 2018Review
- Prevalence of Oral Clefts among Live Births in Gansu Province, China.International journal of environmental research and public health · 2018Article
- Economic valuation of the impact of a large surgical charity using the value of lost welfare approach.BMJ global health · 2016Article
- Surgical rehabilitation of cleft lip and/or palate: evaluation of the Brazilian public health system.Brazilian journal of otorhinolaryngologyArticle
- Cleft Lip and Palate Repair Training to Bridge the Gap in Low-Income Countries.The Journal of craniofacial surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study attempts to quantify the burden of disease averted through the global surgical work of a large cleft charity, and estimate the economic impact of this effort over a 10-year period.
methodsAnonymized data of all primary cleft lip and cleft palate procedures in the Smile Train database were analyzed and disability-adjusted life years (DALYs) calculated using country-specific life expectancy tables, established disability weights, and estimated success of surgery and residual disability probabilities; multiple age weighting and discounting permutations were included. Averted DALYs were calculated and gross national income (GNI) per capita was then multiplied by averted DALYs to estimate economic gains.
results548,147 primary cleft procedures were performed in 83 countries between 2001 and 2011. 547,769 records contained complete data available for the study; 58 % were cleft lip and 42 % cleft palate. Averted DALYs ranged between 1.46 and 4.95 M. The mean economic impact ranged between USD 5510 and 50,634 per person. This corresponded to a global economic impact of between USD 3.0B and 27.7B USD, depending on the DALY and GNI values used. The estimated cost of providing these procedures based on an average reimbursement rate was USD 197M (0.7-6.6 % of the estimated impact).
conclusionsThe immense economic gain realized through procedures focused on a small proportion of the surgical burden of disease highlights the importance and cost-effectiveness of surgical treatment globally. This methodology can be applied to evaluate interventions for other conditions, and for evidence-based health care resource allocation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.