ArticleNature reviews. Drug discovery2016
The right dose for every patient: a key step for precision medicine.
Article in Nature reviews. Drug discovery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Multi-omics strategies for biomarker discovery and application in personalized oncology.Molecular biomedicine · 2025Review
- Breast cancer: pathogenesis and treatments.Signal transduction and targeted therapy · 2025Review
- The Convergence of Radiology and Genomics: Advancing Breast Cancer Diagnosis with Radiogenomics.Cancers · 2024Review
- Model-informed precision dosing of vancomycin for rapid achievement of target area under the concentration-time curve: A simulation study.Clinical and translational science · 2023Article
- Characterization of behavioral changes in T-maze alternation from dopamine DPsychopharmacology · 2023Article
- Drug dosage modifications in 24 million in-patient prescriptions covering eight years: A Danish population-wide study of polypharmacy.PLOS digital health · 2023Article
- How can we deliver on the promise of precision medicine in oncology and beyond? A practical roadmap for action.Health science reports · 2023Article
- Better governance starts with better words: why responsible human tissue research demands a change of language.BMC medical ethics · 2022Article
- A Dopamine DThe Journal of pharmacology and experimental therapeutics · 2022Article
- Identification of heptapeptides targeting a lethal bacterial strain in septic mice through an integrative approach.Signal transduction and targeted therapy · 2022Article
- Optimized sampling to estimate vancomycin drug exposure: Comparison of pharmacometric and equation-based approaches in a simulation-estimation study.CPT: pharmacometrics & systems pharmacology · 2022Article
- Reinforcement learning and Bayesian data assimilation for model-informed precision dosing in oncology.CPT: pharmacometrics & systems pharmacology · 2021Article
- What Does it Take to Make Model-Informed Precision Dosing Common Practice? Report from the 1st Asian Symposium on Precision Dosing.The AAPS journal · 2019Article
- Engineering Precision Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Review
- Drug-Induced Rhabdomyolysis Atlas (DIRA) for idiosyncratic adverse drug reaction management.Drug discovery today · 2019Review
- Paclitaxel Response Can Be Predicted With Interpretable Multi-Variate Classifiers Exploiting DNA-Methylation and miRNA Data.Frontiers in genetics · 2019Article
- Personalized Integrated Network Modeling of the Cancer Proteome Atlas.Scientific reports · 2018Article
- Precision Medicine with Imprecise Therapy: Computational Modeling for Chemotherapy in Breast Cancer.Translational oncology · 2018Review
- Breast cancer: The translation of big genomic data to cancer precision medicine.Cancer science · 2018Review
- Prediction of olanzapine exposure in individual patients using physiologically based pharmacokinetic modelling and simulation.British journal of clinical pharmacology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the basis of variability in the response of patients to the dose of a drug and a willingness to vary the dose regimen as well as the choice of drug should be one of the key pillars of precision medicine.
Indexed as
Identifiers
26669674What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.