Evidence map›Paper›PMID 26669226›Full record

Trial reportJournal of addictions nursing

Different Subjective and Objective Responses to Alcohol Among Heavy and Light Drinkers of Han and Uyghur Nationalities in China.

Hong-Xing Hu, Guan-Bai Zang, Zao-Lin Liu, Sandra Yu Rueger, Patrick McNamara, Andrea C King, Wei Hao

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of addictions nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Hong-Xing HuHong-Xing Hu, MD, Guan-Bai Zang, MD, and Wei Hao, MD, Mental Health Institute, Second Xiangya Hospital, Central South University, Hunan, China. Hong-Xing Hu, MD, Clinical Psychological Department, First Affiliated Hospital, Xinjiang Medical University, China. Zao-Lin Liu, MD, School of Public Health, Xinjiang Medical University, China. Sandra Yu Rueger, MD, Patrick Mc Namara, MD, and Andrea C. King, MD, Department of Psychiatry and Behavioral Neuroscience, University of Chicago, IL.
Guan-Bai Zang
Zao-Lin Liu
Sandra Yu Rueger
Patrick McNamara
Andrea C King
Wei Hao
University of Chicago · USCentral South University · CN

Funding

Alcohol Stimulation and Sedation in Binge Drinkers - Renewal 01R01AA013746 · NIAAA · UNIVERSITY OF CHICAGO · PI DANIEL J FRIDBERG, ANDREA C KING · 2003 to 2026
$11.6M
NIAAA NIH HHS R01 AA013746
6 · The paper itself

Abstract

objectiveGiven the observed differences in alcohol consumption characteristics between the Han and Uyghur nationalities in clinical reports and in daily life, the subjective and objective responses to alcohol in heavy drinkers (HDs) and light drinkers (LDs) in the Han and Uyghur nationalities in China were compared.

methodsA within-subject, double-blind, placebo-controlled human laboratory paradigm was performed. Each subject completed three experimental sessions in random order. Biphasic Alcohol Effects Scale and Positive and Negative Affect Schedule scales were administered, and heart rate (HR), blood pressure, and salivary cortisol levels were measured at predrink baseline and 30, 60, 120, and 180 minutes after the initial alcohol beverage consumption.

resultsCompared with LDs, HDs exhibited higher stimulation, positive affect, and lower sedation in both ethnicities. Han drinkers (both HDs and LDs) exhibited higher sedation and lower positive affect and stimulation than Uyghur drinkers after consumption of alcohol. Moreover, HDs exhibited more HR increase during the ascending limb of breath alcohol content (p < .05) and less cortisol level during the declining limb of breath alcohol content (p < .05). Both HDs and LDs exhibited decreased systolic and diastolic pressures for both high- and low-dose beverages (ps < .01).

conclusionCompared with LDs, HDs exhibited more HR increase and lower salivary cortisol level after alcohol consumption. Han drinkers (both HDs and LDs) exhibited higher sedation and lower positive affect and stimulation after consumption of alcohol as compared with Uyghur drinkers. This modality of subjective and physiological responses to alcohol in the Han and Uyghur ethnicities is similar.

Indexed as

AdultAlcohol DrinkingBlood PressureChinaDouble-Blind MethodEthnicityHeart RateHumansHydrocortisoneMaleSalivaSeverity of Illness IndexYoung AdultHydrocortisone

Identifiers

PMID26669226
PMCPMC5693392
OpenAlexW2428084773

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.