ArticleIranian journal of microbiology2015
The antibacterial effect of sage extract (Salvia officinalis) mouthwash against Streptococcus mutans in dental plaque: a randomized clinical trial.
Article in Iranian journal of microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 53 citations in OpenAlex.
- Results of a randomized controlled phase III trial: efficacy of polyphenol-containing cystus® tea mouthwash solution for the reduction of mucositis in head and neck cancer patients undergoing external beam radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021Trial
- Composites Based on Collagen, Chondroitin Sulfate, and Sage Oil with Potential Use in Dentistry.Biomimetics (Basel, Switzerland) · 2025Article
- Targeting Oral Pathogens withAntibiotics (Basel, Switzerland) · 2025Article
- Balancing the Oral Redox State: Endogenous and Exogenous Sources of Reactive Oxygen Species and the Antioxidant Role of Lamiaceae and Asteraceae.Dentistry journal · 2025Review
- An Ethnopharmacological Survey on Medicinally Important Plants of Genus Salvia.Combinatorial chemistry & high throughput screening · 2025Review
- Exploring the therapeutic potential of medicinal plants and their active principles in dental care: A comprehensive review.Heliyon · 2024Review
- Herbal Mouthrinses for Prevention of Dental Caries in Children and Adolescents: A Systematic Review.International journal of clinical pediatric dentistry · 2024Article
- Natural Compounds ofBiomedicines · 2023Review
- Article
- A systematic review of medicinal plants and herbal products' effectiveness in oral health and dental cure with health promotion approach.Journal of education and health promotion · 2023Review
- Identification of herbal teas and their compounds eliciting antiviral activity against SARS-CoV-2 in vitro.BMC biology · 2022Article
- Propolis, Aloe Vera, Green Tea, Cranberry, Calendula, Myrrha and Salvia Properties against Periodontal Microorganisms.Microorganisms · 2022Review
- The effect of various extraction techniques on the quality of sage (Food chemistry: X · 2022Article
- Can Plant Materials Be Valuable in the Treatment of Periodontal Diseases? Practical Review.Pharmaceutics · 2021Review
- Evaluation of Preventive Antibacterial Properties of a Glass-Ionomer Cement Containing Purified Powder ofInternational journal of preventive medicine · 2019Article
- Antimicrobial effect of Pistacia atlantica leaf extract.Bioinformation · 2016Article
- Antimicrobial effectiveness of aqueous and alcoholic herbal extracts onAvicenna journal of phytomedicineReview
- AnDental research journalArticle
- The comparison of antimicrobial effects of herbal and chemical agents on toothpaste: An experimental study.Dental research journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveThe aim of the study was to evaluate the clinical effects of a mouthwash containing Sage (Salvia officinalis) extracts on Streptococcus mutans (SM) causing dental plaque in school-aged children. MATERIAL AND
methodsA double blind clinical trial study was conducted in a dormitory on 70 girls aged 11-14 years having the same socioeconomic and oral hygiene conditions. These students were randomly divided into 2 groups; the first group (N=35) using Sage mouthwash, and the second group (N=35) using placebo mouthwash without active any ingredients. At the baseline, plaque samples obtained from the buccal surfaces of teeth were sent to laboratory to achieve SM colony count. These tests were reevaluated after 21 days of using the mouthwashes. Statistical data analysis was performed using t-student tests with p<0.05 as the level of significance.
resultsSage mouthwash significantly reduced the colony count (P=0.001). Average number of colonies in test group was 3900 per plaque sample at the baseline, and 300 after mouthwash application. In the control group, pre-test colony count was 4400 that was reduced to 4000; although this reduction wasn't significant.
conclusionThe Sage mouthwash effectively reduced the number of Streptococcus mutans in dental plaque.
Indexed as
Identifiers
26668706PMC4676988W1785455661What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.