Evidence map›Paper›PMID 26668592›Full record

ArticleExperimental and therapeutic medicine2015

Establishment of a rat model for osteoarthritis resulting from anterior cruciate ligament rupture and its significance.

Xiao Ouyang, Jian Wang, Shi Dong Hong, Feng Xin, Lin Wang, Xiao Wei Yang, Jing Rong Wang, Li Ming Wang, B O Wei, Qing Wang and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. A Macaca Fascicularis Knee Osteoarthritis Model Developed by Modified Hulth Combined with Joint Scratches.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xiao OuyangDepartment of Orthopedics, Xuzhou Third People's Hospital, Jiangsu University, Xuzhou, Jiangsu 221005, P.R. China.
Jian WangHospital Administration Offices, Xuzhou Third People's Hospital, Jiangsu University, Xuzhou, Jiangsu 221005, P.R. China.
Shi Dong HongDepartment of Orthopedics, Xuzhou Third People's Hospital, Jiangsu University, Xuzhou, Jiangsu 221005, P.R. China.
Feng XinDepartment of Orthopedics, Xuzhou Third People's Hospital, Jiangsu University, Xuzhou, Jiangsu 221005, P.R. China.
Lin WangDepartment of Orthopedics, Xuzhou Third People's Hospital, Jiangsu University, Xuzhou, Jiangsu 221005, P.R. China.
Xiao Wei YangDepartment of Orthopedics, Xuzhou Third People's Hospital, Jiangsu University, Xuzhou, Jiangsu 221005, P.R. China.
Jing Rong WangDepartment of Orthopedics, Xuzhou Third People's Hospital, Jiangsu University, Xuzhou, Jiangsu 221005, P.R. China.
Li Ming WangDepartment of Orthopedics, Xuzhou Third People's Hospital, Jiangsu University, Xuzhou, Jiangsu 221005, P.R. China ; Department of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, P.R. China.
B O WeiDepartment of Orthopedics, Xuzhou Third People's Hospital, Jiangsu University, Xuzhou, Jiangsu 221005, P.R. China ; Department of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, P.R. China.
Qing WangDepartment of Orthopedics, Xuzhou Third People's Hospital, Jiangsu University, Xuzhou, Jiangsu 221005, P.R. China ; Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Wei Ding CuiDepartment of Orthopedics, Xuzhou Third People's Hospital, Jiangsu University, Xuzhou, Jiangsu 221005, P.R. China ; Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Xuzhou Cancer Hospital · CNJiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to examine the establishment of a model concerned with osteoarthritis resulting from the anterior cruciate ligament rupture of rats and investigate the associated mechanism, as well as provide a theoretical basis for clinical treatment of the disease. Forty Sprague-Dawley male rats were randomly divided into two groups of 20 rats each and the anterior cruciate ligament transaction model and knee joint brake model were successfully established. Two rats in the anterior cruciate ligament transection group (10%) and 3 rats in the knee joint brake group (15.0%) died. The survival rate of the two groups was not statistically significant (χ

Indexed as

anterior cruciate ligament ruptureII collagen fiberknee joint brakeosteoarthritis modelproteoglycan

Identifiers

PMID26668592
PMCPMC4665123
OpenAlexW2110329209

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.