Evidence map›Paper›PMID 26668481›Full record

ArticleJournal of international oral health : JIOH2015

Assessment of Systemic Inflammatory Markers in Patients with Aggressive Periodontitis.

P Safar Iqbal, S Nubesh Khan, Mohamed Haris, Mahesh Narayanan, S Laju, Swaminathan Senthil Kumar

Open access · greenAbstract read
In one paragraph

Article in Journal of international oral health : JIOH, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

P Safar IqbalAssistant Professor, Department of Periodontics, Malabar Dental College, Kerala, India.
S Nubesh KhanAssistant Professor, Department of Periodontics, Sri Sankara Dental College, Kerala, India.
Mohamed HarisAssistant Professor, Department of Oral Pathology, Malabar Dental College, Kerala, India.
Mahesh NarayananProfessor and HOD, Department of Periodontics, Malabar Dental College, Kerala, India.
S LajuAssociate Professor, Department of Prosthodontics, Malabar Dental College, Kerala, India.
Swaminathan Senthil KumarProfessor, Department of Periodontics, Rajah Muthiah Dental College & Hospital, Tamil Nadu, India.
Malabar Medical College Hospital and Research Centre · INNoorul Islam College of Dental Science · INRagas Dental College & Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background"Aggressive periodontitis (AgP) is a destructive disease characterized by the following: The involvement of multiple teeth with a distinctive pattern of periodontal tissue loss; a high rate of disease progression; an early age of onset; and the absence of systemic diseases.'' Chronic low-level bacteremia and systemic inflammatory response have been suggested as a pathogenic link between periodontal disease and systemic disease. The present study was aimed to assess the levels of systemic inflammatory markers in patients with AgP.

methodsA sample of 50 systemically healthy patients comprised two groups, based on full mouth periodontal examination: Group I healthy individuals, includes 25 periodontally healthy subjects with fully functioning dentition. Group II includes 25 patients diagnosed clinically as AgP. Laboratory blood investigation included white blood cell (WBC) count, neutrophil count, lymphocyte count, and platelet count. Serum protein parameters included total protein (TP), albumin (ALB), and globulin (GLB). Periodontal clinical parameters including plaque index, gingival index, probing pocket depth, and clinical attachment level were recorded.

resultsData analysis shows an increase in WBC, neutrophil, lymphocyte, and platelet count and a decrease in TP, ALB, and GLB in AgP patients when compared to healthy individuals.

conclusionResults of the present study shows an increase in blood parameters and decrease in serum protein parameters in AgP. Hence, AgP could be considered as one of the risk factors associated with the cardiovascular diseases as assessed by changes in the level of systemic inflammatory markers observed.

Indexed as

Aggressive periodontitisbacteremiainflammationsystemic circulation

Identifiers

PMID26668481
PMCPMC4672851
OpenAlexW2410103306

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.