Evidence map›Paper›PMID 26667317›Full record

ArticleBasic research in cardiology2016

Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside.

Hector A Cabrera-Fuentes, Corina Alba-Alba, Julian Aragones, Jürgen Bernhagen, William A Boisvert, Hans E Bøtker, Gabriela Cesarman-Maus, Ingrid Fleming, David Garcia-Dorado, Sandrine Lecour and 17 more

Abstract readConference Proceedings
In one paragraph

Article in Basic research in cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Obesity subtypes, related biomarkers & heterogeneity.The Indian journal of medical research · 2020
    Review
  9. Article
  10. Involvement of Endothelin-1, HCellular and molecular neurobiology · 2019
    Article
  11. Role of Macrophages in Cardioprotection.International journal of molecular sciences · 2019
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Secretome of IntestinalFrontiers in microbiology · 2017
    Review
  17. Review
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  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Hector A Cabrera-FuentesInstitute of Biochemistry, Medical School, Justus-Liebig University, Giessen, Germany.
Corina Alba-AlbaInstitute of Genetics, Univeristy of the Sea. Puerto Escondido Campus, Oaxaca Oaxacan System of State Universities (SUNEO), Oaxaca, México.
Julian AragonesResearch Unit, Hospital of Santa Cristina, Research Institute Princesa (IP), Autonomous University of Madrid, Madrid, Spain.
Jürgen BernhagenInstitute of Biochemistry and Molecular Cell Biology, RWTH Aachen University, Aachen, Germany.
William A BoisvertDepartment of Microbiology, Kazan Federal University, Kazan, Russian Federation.
Hans E BøtkerDepartment of Cardiology, Aarhus University Hospital, Skejby, Aarhus N, Denmark.
Gabriela Cesarman-MausDepartment of Hematology, Instituto Nacional de Cancerología, Mexico City, Mexico.
Ingrid FlemingInstitute for Vascular Signalling, Centre for Molecular Medicine, Goethe-University, Frankfurt, Germany.
David Garcia-DoradoValld'Hebron University Hospital and Research Institute, Barcelona, Spain.
Sandrine LecourHatter Institute and MRC Inter-University Cape Heart Unit, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Elisa LiehnInstitute for Molecular Cardiovascular Research, RWTH University Hospital Aachen, Aachen, Germany.
Michael S MarberDepartment of Cardiology, The Rayne Institute, St Thomas' Campus, King's College London, London, UK.
Nephtali MarinaDepartment of Clinical Pharmacology, University College London, London, UK.
Manuel MayrThe James Black Centre, King's College, University of London, London, UK.
Oscar Perez-MendezDepartment of Molecular Biology, National Institute of Cardiology, Mexico City, Mexico.
Tetsuji MiuraDepartment of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
Marisol Ruiz-MeanaValld'Hebron University Hospital and Research Institute, Barcelona, Spain.
Eduardo M Salinas-EstefanonLaboratorio de Biofísica Cardiaca, Instituto de Fisiología, Universidad Autónoma de Puebla, Puebla, Mexico.
Sang-Bing OngCardiovascular and Metabolic Disorders Program, Duke-National University of Singapore, Singapore, Singapore.
Hans J SchnittlerInstitute of Anatomy and Vascular Biology, Westfalian-Wilhelms-University, Münster, Germany.
Jose T Sanchez-VegaLaboratory of Parasitology, Department of Microbiology and Parasitology, Faculty of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Adriana Sumoza-ToledoLaboratorio Multidisciplinario de Ciencias Biomédicas, Instituto de Investigaciones Medico-Biológicas, Universidad Veracruzana campus Veracruz, Veracruz, Mexico.
Carl-Wilhelm VogelDepartment of Pathology, John A. Burns School of Medicine, University of Hawaii, Honolulu, USA.
Dina YarullinaDepartment of Microbiology, Kazan Federal University, Kazan, Russian Federation.
Derek M YellonThe Hatter Cardiovascular Institute, University College London, London, UK.
Klaus T PreissnerInstitute of Biochemistry, Medical School, Justus-Liebig University, Giessen, Germany.
Derek J HausenloyCardiovascular and Metabolic Disorders Program, Duke-National University of Singapore, Singapore, Singapore. derek.hausenloy@duke-nus.edu.sg.

Funding

Pilot Project ProgramP30GM103341 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI SHOHET, RALPH V. · 2012 to 2016
$5.5M
Anti-inflammatory Cytokines in AtherosclerosisR01HL075677 · NHLBI · UNIVERSITY OF HAWAII AT MANOA · PI BOISVERT, WILLIAM A · 2005 to 2008
$1.6M
Rho kinase in immune-mediated atherosclerosisR01HL081863 · NHLBI · UNIVERSITY OF HAWAII AT MANOA · PI BOISVERT, WILLIAM A · 2007 to 2010
$1.6M
British Heart Foundation FS/13/2/29892British Heart Foundation FS/13/5/29927British Heart Foundation SP/12/5/29574British Heart Foundation TG/15/1/31518Medical Research Council G1000737NHLBI NIH HHS R01 HL075677NHLBI NIH HHS R01 HL081863NIGMS NIH HHS P30 GM103341
6 · The paper itself

Abstract

Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last "New Frontiers in Cardiovascular Research meeting". Major topics included the characterization of new targets and procedures in cardioprotection, deciphering new players and inflammatory mechanisms in ischemic heart disease as well as uncovering microRNAs and other biomarkers as versatile and possibly causal factors in cardiovascular pathogenesis. Although a number of pathological situations such as ischemia-reperfusion injury or atherosclerosis can be simulated and manipulated in diverse animal models, also to challenge new drugs for intervention, patient studies are the ultimate litmus test to obtain unequivocal information about the validity of biomedical concepts and their application in the clinics. Thus, the open and bidirectional exchange between bench and bedside is crucial to advance the field of ischemic heart disease with a particular emphasis of understanding long-lasting approaches in cardioprotection.

Indexed as

Cardiovascular DiseasesTranslational Research, BiomedicalAnimalsHumansAtherosclerosisCardioprotectionCardiovascular diseaseEndothelial permeabilityExtracellular RNAHigh-density lipoproteinHypoxiaInflammationIschemia/reperfusion injuryMacrophage polarizationMicroRNAsMitochondriaPlatelet dysfunctionVascular biology

Identifiers

PMID26667317
PMCPMC4679108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.