ReviewAnnual review of entomology2016
Reproduction-Immunity Trade-Offs in Insects.
Review in Annual review of entomology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 288 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
288 citing papers in PubMed, 1 synthesis or guideline pooled it, 660 citations in OpenAlex.
- Host-pathogen interactions under pressure: A review and meta-analysis of stress-mediated effects on disease dynamics.Ecology letters · 2023Pooled it
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- Uracil-driven ROS signaling and larval TrpA1-B neuron activation are required for priming the adult Drosophila gustatory response to bacteria.PLoS biology · 2026Article
- The Adult Aedes aegypti Bacterial Microbiota is Robust to Infection with the Obligate Microsporidian Parasite Edhazardia aedis.Environmental microbiology · 2026Article
- Male and Female Cat Fleas (Insects · 2026Article
- Transcriptomic Landscape Reveals Immunity Related Trade-Offs in an Invertebrate-Fungal Host-Parasite System.Molecular ecology · 2026Article
- Comparative analyses of the Serratia marcescens complex reveal variations in their pathogenicity against a fruit pest.Pest management science · 2026Article
- Eco-Evolutionary Dynamics of Proliferation Heterogeneity: A Phenotype-Structured Model for Tumor Growth and Treatment Response.Bulletin of mathematical biology · 2026Article
- Article
- Reduced 20-Hydroxyecdysone Signaling Modulates Antifungal Immune Responses and Growth inInsects · 2026Article
- Early Post-Eclosion Physiological Remodelling inInsects · 2026Article
- Transcriptional Reshaping of Bacteriocytes in the Aphid-Insects · 2026Article
- Placental crises: disruptive selection and maternal under-investment as the foundations of mammalian placental evolution and dysfunction.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Juvenile hormone signaling acts during development and post-mating to suppress antibacterial defenses in Drosophila melanogaster.Scientific reports · 2026Article
- Immune-reproductive cross talk in mosquitoes: molecular pathways and energy homeostasis.Parasites & vectors · 2026Review
- Sex differences inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Cestode infection is linked to transcriptional shifts in neuropeptide signalling and caste-specific ageing pathways in a social insect.BMC genomics · 2026Article
- Tissue-specific transcriptomic analysis of accelerated reproductive development of immature Queensland fruit fly induced by raspberry ketone ingestion.BMC genomics · 2026Article
- Antioxidant, Redox, and Immunomodulatory Effects ofBiomedicines · 2026Article
- Article
228 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
Abstract
Immune defense and reproduction are physiologically and energetically demanding processes and have been observed to trade off in a diversity of female insects. Increased reproductive effort results in reduced immunity, and reciprocally, infection and activation of the immune system reduce reproductive output. This trade-off can manifest at the physiological level (within an individual) and at the evolutionary level (genetic distinction among individuals in a population). The resource allocation model posits that the trade-off arises because of competition for one or more limiting resources, and we hypothesize that pleiotropic signaling mechanisms regulate allocation of that resource between reproductive and immune processes. We examine the role of juvenile hormone, 20-hydroxyecdysone, and insulin/insulin-like growth factor-like signaling in regulating both oogenesis and immune system activity, and propose a signaling network that may mechanistically regulate the trade-off. Finally, we discuss implications of the trade-off in an ecological and evolutionary context.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.