ArticleScientific reports2015
Effect of handedness on brain activity patterns and effective connectivity network during the semantic task of Chinese characters.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
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- [Study on brain mechanism of rehabilitation training of articulation disorder in cleft lip and palate patients based on functional magnetic resonance imaging].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023Article
- A review of functional MRI application for brain research of Chinese language processing.Magnetic resonance letters · 2023Review
- Reading-related Brain Function Restored to Normal After Articulation Training in Patients with Cleft Lip and Palate: An fMRI Study.Neuroscience bulletin · 2022Article
- Brain Anatomy Alterations and Mental Health Challenges Correlate to Email Addiction Tendency.Brain sciences · 2022Article
- Abnormal Prefrontal Functional Connectivity Is Associated with Inflexible Information Processing in Patients with Autism Spectrum Disorder (ASD): An fNIRS Study.Biomedicines · 2022Article
- Aberrant prefrontal functional connectivity during verbal fluency test is associated with reading comprehension deficits in autism spectrum disorder: An fNIRS study.Frontiers in psychology · 2022Article
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- Sex, Age, and Handedness Modulate the Neural Correlates of Active Learning.Frontiers in neuroscience · 2019Article
- Language lateralization during the Chinese semantic task relates to the contralateral cerebra-cerebellar interactions at rest.Scientific reports · 2017Article
- The Impact of Aerobic Exercise on Fronto-Parietal Network Connectivity and Its Relation to Mobility: An Exploratory Analysis of a 6-Month Randomized Controlled Trial.Frontiers in human neuroscience · 2017Article
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4 authors.
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Abstract
Increasing efforts have been denoted to elucidating the effective connectivity (EC) among brain regions recruited by certain language task; however, it remains unclear the impact of handedness on the EC network underlying language processing. In particularly, this has not been investigated in Chinese language, which shows several differences from alphabetic language. This study thereby explored the functional activity patterns and the EC network during a Chinese semantic task based on functional MRI data of healthy left handers (LH) and right handers (RH). We found that RH presented a left lateralized activity pattern in cerebral cortex and a right lateralized pattern in cerebellum; while LH were less lateralized than RH in both cerebral and cerebellar areas. The conditional Granger causality method in deconvolved BOLD level further demonstrated more interhemispheric directional connections in LH than RH group, suggesting better bihemispheric coordination and increased interhemispheric communication in LH. Furthermore, we found significantly increased EC from right middle occipital gyrus to bilateral insula (INS) while decreased EC from left INS to left precentral gyrus in LH group comparing to RH group, implying that handedness may differentiate the causal relationship of information processing in integration of visual-spatial analysis and semantic word retrieval of Chinese characters.
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