ArticleThe American journal of tropical medicine and hygiene2016
Viremia in North American Mammals and Birds After Experimental Infection with Chikungunya Viruses.
Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Advances and perspectives for animal models of chikungunya virus infection.Biosafety and health · 2025Review
- Serologic Surveillance for Orthoflaviviruses and Chikungunya Virus in Bats and Opossums in Chiapas, Mexico.Viruses · 2025Article
- Facile quantitative diagnostic testing for neutralizing antibodies against Chikungunya virus.BMC infectious diseases · 2024Article
- Serosurvey of Chikungunya Virus in Old World Fruit Bats, Senegal, 2020-2022.Emerging infectious diseases · 2024Article
- Species-specific MARCO-alphavirus interactions dictate chikungunya virus viremia.Cell reports · 2023Article
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- Pirahy virus: Identification of a new and potential emerging arbovirus in South Brazil.Virus evolution · 2021Article
- Mosquito-bite infection of humanized mice with chikungunya virus produces systemic disease with long-term effects.PLoS neglected tropical diseases · 2021Article
- An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis.Cell host & microbe · 2020Article
- Can Bats Serve as Reservoirs for Arboviruses?Viruses · 2019Review
- Tropism of the Chikungunya Virus.Viruses · 2019Review
- Serological evidence of widespread exposure of Grenada fruit bats to chikungunya virus.Zoonoses and public health · 2018Article
- Role of monkeys in the sylvatic cycle of chikungunya virus in Senegal.Nature communications · 2018Article
- Reptiles and Amphibians as Potential Reservoir Hosts of Chikungunya Virus.The American journal of tropical medicine and hygiene · 2018Article
- Mosquito-Associated Viruses in China.Virologica Sinica · 2018Review
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Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chikungunya virus (CHIKV) is an arthropod-borne virus, which is known to cause severe disease only in humans. To investigate its potential zoonotic host range and evaluate reservoir competence among these hosts, experimental infections were performed on individuals from nine avian and 12 mammalian species representing both domestic and wild animals common to North America. Hamsters and inbred mice have previously been shown to develop viremia after inoculation with CHIKV and were used as positive controls for infection. Aside from big brown bats (Eptesicus fuscus), none of the mammals or birds developed detectable viremia or overt clinical disease. However, most mammals and a smaller proportion of birds developed neutralizing antibody responses to CHIKV. On the basis of these results, it seems unlikely that CHIKV poses a significant health threat to most domestic animals or wildlife and that the species examined do not likely contribute to natural transmission cycles. Additional studies should further evaluate bats and wild rodents as potential reservoir hosts for CHIKV transmission during human epidemics.
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