ArticleBMC genomics2015
ChromContact: A web tool for analyzing spatial contact of chromosomes from Hi-C data.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Mitochondrial stress induces AREG expression and epigenomic remodeling through c-JUN and YAP-mediated enhancer activation.Nucleic acids research · 2022Article
- 3DIV: A 3D-genome Interaction Viewer and database.Nucleic acids research · 2018Article
- A deletion in the intergenic region upstream of Ednrb causes head spot in the rat strain KFRS4/Kyo.BMC genetics · 2017Article
- A cautionary note on the use of chromosome conformation capture in plants.Plant methods · 2017Article
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Authors and funding
2 authors.
Funding
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Abstract
backgroundHi-C analysis has revealed the three-dimensional architecture of chromosomes in the nucleus. Although Hi-C data contains valuable information on long-range interactions of chromosomes, the data is not yet widely utilized by molecular biologists because of the quantity of data.
resultsWe developed a web tool, ChromContact, to utilize the information obtained by Hi-C. The web tool is designed to be simple and easy to use. By specifying a locus of interest, ChromContact calculates contact profiles and generates links to the UCSC Genome Browser, enabling users to visually examine the contact information with various annotations.
conclusionChromContact provides wide-range of molecular biologists with a user-friendly means to access high-resolution Hi-C data. One of the possible applications of ChromContact is investigating novel long-range promoter-enhancer interactions. This facilitates the functional interpretation of statistically significant markers identified by GWAS or ChIP-seq peaks that are located far from any annotated genes. ChromContact is freely accessible at http://bioinfo.sls.kyushu-u.ac.jp/chromcontact/ .
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