Evidence map›Paper›PMID 26666508›Full record

ArticleSpinal cord2016

Effects of aerobic exercise training on fitness and walking-related outcomes in ambulatory individuals with chronic incomplete spinal cord injury.

N D DiPiro, A E Embry, S L Fritz, A Middleton, J S Krause, C M Gregory

Abstract read
In one paragraph

Article in Spinal cord, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Effectiveness of aerobic physical training for spinal cord injury rehabilitation: A mini-review.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2026
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Inflammatory Stress Effects on Health and Function After Spinal Cord Injury.Topics in spinal cord injury rehabilitation · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

N D DiPiroDepartment of Health Sciences and Research, Medical University of South Carolina, Charleston, SC, USA.
A E EmbryDepartment of Health Sciences and Research, Medical University of South Carolina, Charleston, SC, USA.
S L FritzDepartment of Exercise Science, Physical Therapy Program, University of South Carolina, Columbia, SC, USA.
A MiddletonDepartment of Exercise Science, Physical Therapy Program, University of South Carolina, Columbia, SC, USA.
J S KrauseDepartment of Health Sciences and Research, Medical University of South Carolina, Charleston, SC, USA.
C M GregoryDepartment of Health Sciences and Research, Medical University of South Carolina, Charleston, SC, USA.

Funding

Treating Depression and Enhancing Locomotor Recovery Post-strokeP20GM109040 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2014 to 2024
$23.5M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR000062 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2012 to 2014
$9.4M
Biomedical-Behavioral Interface: Prevention and Developmental Sciences TrainingT32GM081740 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI PRINZ, RONALD J · 2008 to 2022
$4.5M
South Carolina Clinical & Translational Research Institute (SCTR)TL1TR000061 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2012 to 2014
$483k
NCATS NIH HHS TL1 TR000061NCATS NIH HHS UL1 TR000062NIGMS NIH HHS P20 GM109040NIGMS NIH HHS T32 GM081740
6 · The paper itself

Abstract

STUDY

designSingle group, pretest-post-test study.

objectivesTo determine the effects of a non-task-specific, voluntary, progressive aerobic exercise training (AET) intervention on fitness and walking-related outcomes in ambulatory adults with chronic motor-incomplete SCI.

settingRehabilitation research center.

methodsTen ambulatory individuals (50% female; 57.94±9.33 years old; 11.11±9.66 years postinjury) completed voluntary, progressive moderate-to-vigorous intensity AET on a recumbent stepper 3 days per week for 6 weeks. The primary outcome measures were aerobic capacity (VO2peak (volume of oxygen that the body can use during physical exertion)) and self-selected overground walking speed (OGWS). Secondary outcome measures included walking economy, 6-minute walk test (6MWT), daily step counts, Walking Index for Spinal Cord Injury (WISCI-II), Dynamic Gait Index (DGI) and Berg Balance Scale (BBS).

resultsNine participants completed all testing and training. Significant improvements in aerobic capacity (P=0.011), OGWS (P=0.023), the percentage of VO2peak used while walking at self-selected speed (P=0.03) and daily step counts (P=0.025) resulted following training.

conclusionsThe results indicate that total-body, voluntary, progressive AET is safe, feasible, and effective for improving aerobic capacity, walking speed, and select walking-related outcomes in an exclusively ambulatory SCI sample. This study suggests the potential for non-task-specific aerobic exercise to improve walking following incomplete SCI and builds a foundation for further investigation aimed at the development of exercise based rehabilitation strategies to target functionally limiting impairments in ambulatory individuals with chronic SCI.

Indexed as

AdolescentAdultAgedChronic DiseaseDisability EvaluationExerciseExercise TherapyFemaleGait Disorders, NeurologicHumansMaleMiddle AgedRecovery of FunctionRehabilitation CentersSpinal Cord InjuriesStatistics, Nonparametric

Identifiers

PMID26666508
PMCPMC4909592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.