Evidence map›Paper›PMID 26666301›Full record

Trial reportBMC health services research2015

The systematic early integration of palliative care into multidisciplinary oncology care in the hospital setting (IPAC), a randomized controlled trial: the study protocol.

Gaëlle Vanbutsele, Simon Van Belle, Martine De Laat, Veerle Surmont, Karen Geboes, Kim Eecloo, Koen Pardon, Luc Deliens

Registry-linked trialAbstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in BMC health services research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01865396 (Effect of Early Palliative Care on Quality of Life of Patients With Advanced Cancer), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01865396 nacompletednot on this map

Effect of Early Palliative Care on Quality of Life of Patients With Advanced Cancer: a Randomised Controlled Trial.

TypeinterventionalSponsorUniversity GhentRan2013 to 2017Enrolled268ConditionsLife-limiting Cancer With Prognosis of Approximately 1 YearArmsInterventional palliative care, Standard oncologic care
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Early palliative care for adults with advanced cancer.The Cochrane database of systematic reviews · 2017
    Pooled it
  3. The development of local outpatient palliative care referral criteria for persons with advanced cancer at the University Hospital Centre Zagreb: a Delphi study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Article
  6. Early Palliative Care for Oncology Patients: How APRNs Can Take the Lead.Journal of the advanced practitioner in oncology · 2021
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gaëlle VanbutseleEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Ghent University, Laarbeeklaan 103, 1090, Brussels, Belgium. gaelle.vanbutsele@uzgent.be.
Simon Van BelleEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Ghent University, Laarbeeklaan 103, 1090, Brussels, Belgium.
Martine De LaatPalliative care team, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Veerle SurmontDepartment of Respiratory Medicine/Thoracic Oncology, Ghent University Hospital, De Pintelaan 185, Ghent, Belgium.
Karen GeboesDepartment of Gastroenterology, Division of Digestive Oncology, Ghent University Hospital, De Pintelaan 185, Ghent, Belgium.
Kim EeclooEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Ghent University, Laarbeeklaan 103, 1090, Brussels, Belgium.
Koen PardonEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Ghent University, Laarbeeklaan 103, 1090, Brussels, Belgium.
Luc DeliensEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Ghent University, Laarbeeklaan 103, 1090, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies in the US and Canada, have shown the positive impact of early palliative care programs for advanced cancer patients on quality of life (QoL) and even survival time. There has been a lack of similar research in Europe. In order to generalize the findings from the US and Canada research on a larger scale, similar studies are needed in different countries with different care settings. The aim of this paper is to describe the research protocol of a randomized controlled trial, situated in Flanders, Belgium, evaluating the effect of systematic early integration of palliative care in standard oncology care. METHODS/

designA randomized controlled trial will be conducted as follows: 182 patients with advanced cancer will be recruited from the departments of Medical Oncology, Digestive Oncology and Thoracic Oncology of the Ghent University Hospital. The trial will randomize patients to either systematic early integration of palliative care in standard oncology care or standard oncology care alone. Patients and informal caregivers will be asked to fill out questionnaires on QoL, mood, illness understanding and satisfaction with care at baseline, 12 weeks and every six weeks thereafter. Other outcome measures are end-of-life care decisions and overall survival time. DISCUSSION: This trial will be the first randomized controlled trial in the Belgian health care setting to evaluate the effect of systematic early integration of palliative care for advanced cancer patients. The results will enable us to evaluate whether systematic early integration of palliative care has positive effects on QoL, mood and patient illness-understanding and which components of the intervention contribute to these effects.

trial registrationClinicaltrials.gov Identifier: NCT01865396 , registered 24(th) of May, 2013.

Indexed as

Terminally IllAdaptation, PsychologicalAdultAgedBelgiumCaregiversClinical ProtocolsFemaleHospitalsHumansMaleMiddle AgedNeoplasmsPalliative CarePatient SatisfactionQuality of Life

Identifiers

PMID26666301
PMCPMC4678668

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.