Evidence map›Paper›PMID 26665123›Full record

ArticleAnnals of surgical treatment and research2015

Clinicopathological characteristics and treatment outcomes of 38 cases of primary thyroid lymphoma: a multicenter study.

Young Jun Chai, Jun Hyun Hong, Do Hoon Koo, Hyeong Won Yu, Joon-Hyop Lee, Hyungju Kwon, Su-Jin Kim, June Young Choi, Kyu Eun Lee

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of surgical treatment and research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 61 citations in OpenAlex.

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  11. [Diffuse large B-cell lymphoma of thyroid invading the superior mediastinum with hashimoto's thyroiditis: a case report and literature review].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023
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  16. Primary thyroid lymphoma -- report of four cases and literature review.International journal of clinical and experimental pathology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Young Jun ChaiDepartment of Surgery, Seoul National University Boramae Medical Center, Seoul, Korea. ; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
Jun Hyun HongDepartment of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Do Hoon KooDepartment of Surgery, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
Hyeong Won YuCancer Research Institute, Seoul National University College of Medicine, Seoul, Korea. ; Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Joon-Hyop LeeCancer Research Institute, Seoul National University College of Medicine, Seoul, Korea. ; Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Hyungju KwonCancer Research Institute, Seoul National University College of Medicine, Seoul, Korea. ; Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Su-Jin KimCancer Research Institute, Seoul National University College of Medicine, Seoul, Korea. ; Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
June Young ChoiCancer Research Institute, Seoul National University College of Medicine, Seoul, Korea. ; Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Kyu Eun LeeCancer Research Institute, Seoul National University College of Medicine, Seoul, Korea. ; Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Seoul National University · KRSeoul National University Hospital · KRInje University Haeundae Paik Hospital · KRSeoul National University Bundang Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrimary thyroid lymphoma (PTL) is a rare disease and it has been investigated in a limited number of studies. The present multicenter study evaluated the clinical features and treatment outcomes of PTL.

methodsThe medical records of patients diagnosed with PTL between 2000 and 2013 in three centers were retrospectively reviewed.

resultsThe study included 11 men and 27 women with a median age of 63.3 years (range, 42-83 years). The median follow-up was 56.0 months (range, 3-156 months). Of the 38 patients included, 16 had mucosa-associated lymphoid tissue (MALT) lymphoma, six had mixed MALT and diffuse large B-cell lymphoma (DLBCL), and 16 had DLBCL. Thirty-five patients (92.1%) had early stage (stage I/II) disease. Of the 16 MALT lymphoma patients, 14 were treated by surgery, and radiotherapy (RT) or chemotherapy was combined in five patients. Two patients received RT or chemotherapy alone. Of the six mixed MALT and DLBCL patients, three underwent surgery with chemotherapy and three underwent chemotherapy alone, RT alone, or surgery with RT. All of the 16 DLBCL patients received chemotherapy, and surgery and RT was combined in 4 and 1 patients, respectively. The 5-year survival was 100% for MALT lymphoma (7 of 7) and mixed MALT and DLBCL patients (5 of 5) and 87.5% for DLBCL patients (7 of 8).

conclusionEarly stage PTL has an excellent prognosis when managed by single or combined treatment modalities. Clinicians should consider PTL in patients with underlying Hashimoto's thyroiditis presenting with an enlarging thyroid mass.

Indexed as

Diffuse Large B-cell lymphomaLymphomaMarginal zone B-cell lymphomaPrimary thyroid lymphomaThyroid lymphoma

Identifiers

PMID26665123
PMCPMC4672092
OpenAlexW2185397470

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.