ReviewFrontiers in veterinary science2015
The Genetics of Deafness in Domestic Animals.
Review in Frontiers in veterinary science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 63 citations in OpenAlex.
- LHFPL5 splice site variant in a cat with deafness and vestibular dysfunction.Animal genetics · 2025Article
- Incorporating Morphological Evaluations into Breeding Soundness Examinations for Female Dogs.Animals : an open access journal from MDPI · 2025Review
- Dominant blue eyes in Maine Coon cats: New PAX3 variant and updated phenotypic data.Animal genetics · 2025Article
- Melanin in the Retinal Epithelium and Magnetic Sensing: A Review of Current Studies.Biophysica · 2024Article
- Brainstem auditory evoked responses: Objective hearing threshold assessment in Holstein cows.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2024Article
- A CDH23 missense variant in Beauceron dogs with non-syndromic deafness.Animal genetics · 2023Article
- A chromosome-level genome assembly reveals genomic characteristics of the American mink (Neogale vison).Communications biology · 2022Article
- De-novo and genome-wide meta-analyses identify a risk haplotype for congenital sensorineural deafness in Dalmatian dogs.Scientific reports · 2022Article
- Evaluation of the prevalence of congenital sensorineural deafness in a population of 72 client-owned purebred white cats examined from 2007 to 2021.BMC veterinary research · 2022Article
- Sox10 Gene Is Required for the Survival of Saccular and Utricular Hair Cells in a Porcine Model.Molecular neurobiology · 2022Article
- Congenital malformations of the external and middle ear accompanied by temporal bone anomaly in a calf.The Journal of veterinary medical science · 2022Article
- Early onset adult deafness in the Rhodesian Ridgeback dog is associated with an in-frame deletion in the EPS8L2 gene.PloS one · 2022Article
- Missense variant in LOXHD1 is associated with canine nonsyndromic hearing loss.Human genetics · 2021Article
- Gentamicin-induced sensorineural auditory loss in healthy adult horses.Journal of veterinary internal medicine · 2021Article
- A natural knockout of the MYO7A gene leads to pre-weaning mortality in pigs.Animal genetics · 2021Article
- A Missense Mutation in theGenes · 2021Article
- Article
- Comparison of the efficacy of 2 sedative protocols in pediatric dogs undergoing brainstem auditory-evoked response testing.The Canadian veterinary journal = La revue veterinaire canadienne · 2020Article
- Genomic analysis of the domestication and post-Spanish conquest evolution of the llama and alpaca.Genome biology · 2020Article
- Decline in prevalence of congenital sensorineural deafness in Dalmatian dogs in the United Kingdom.Journal of veterinary internal medicine · 2020Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although deafness can be acquired throughout an animal's life from a variety of causes, hereditary deafness, especially congenital hereditary deafness, is a significant problem in several species. Extensive reviews exist of the genetics of deafness in humans and mice, but not for deafness in domestic animals. Hereditary deafness in many species and breeds is associated with loci for white pigmentation, where the cochlear pathology is cochleo-saccular. In other cases, there is no pigmentation association and the cochlear pathology is neuroepithelial. Late onset hereditary deafness has recently been identified in dogs and may be present but not yet recognized in other species. Few genes responsible for deafness have been identified in animals, but progress has been made for identifying genes responsible for the associated pigmentation phenotypes. Across species, the genes identified with deafness or white pigmentation patterns include MITF, PMEL, KIT, EDNRB, CDH23, TYR, and TRPM1 in dog, cat, horse, cow, pig, sheep, ferret, mink, camelid, and rabbit. Multiple causative genes are present in some species. Significant work remains in many cases to identify specific chromosomal deafness genes so that DNA testing can be used to identify carriers of the mutated genes and thereby reduce deafness prevalence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.