ArticleFrontiers in veterinary science2015
Non-Radiation-Related Osteonecrosis of the Jaws in Dogs: 14 Cases (1996-2014).
Article in Frontiers in veterinary science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 14 citations in OpenAlex.
- Prophylactic antibiotic use is common in dogs and cats presenting for procedures at veterinary referral dental practices.Journal of the American Veterinary Medical Association · 2025Article
- A case series and review of canine idiopathic osteonecrosis of the jaw.Frontiers in veterinary science · 2025Article
- Case report: Management of generalized infection and draining tracts of the frontomaxillary region in a dog.Frontiers in veterinary science · 2024Article
- An update on oral manifestations of systemic disorders in dogs and cats.Frontiers in veterinary science · 2024Review
- Antimicrobial use practices in canine and feline dental procedures performed in primary care veterinary practices in the United States.PloS one · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteonecrosis of the jaws (ONJ) is an entity of major clinical impact characterized by chronically exposed necrotic mandibular or maxillary bone. Its clinicopathological characteristics and possible inciting or risk factors are well described in humans but only anecdotally reported in dogs. Treatment modalities and outcome vary depending on the inciting factors involved and the extent and severity of the lesions. The objectives of this study were to retrospectively describe the clinicopathological features of non-radiation-related ONJ in a series of 14 dogs, identify possible inciting or risk factors, and report on the surgical treatment and outcome. For all patients, the medical records were used to collect information regarding signalment, clinical signs, characteristics of the oral, jaw and dental lesions, diagnostic imaging findings, histopathological and microbiological analysis, treatment performed, and outcome. The data collected showed that non-radiation-related ONJ appears to be an infrequent clinical entity but of significant impact in dogs; that a history of systemic antibiotics and dental disease is common among affected dogs; that previous dental extractions are commonly associated with ONJ sites; that using a systematic diagnostic approach is essential for diagnosis; and that thorough surgical debridement combined with a course of oral antibiotics was effective in the described dogs affected by advanced non-radiation-related ONJ.
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