ArticleFrontiers in cardiovascular medicine2015
Dobutamine-Induced Strain and Strain Rate Predict Viability Following Fibrinolytic Therapy in Patients with ST-Elevation Myocardial Infarction.
Article in Frontiers in cardiovascular medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis.Cancer research · 2025Article
- Visual Assessment and Longitudinal Strain During Dobutamine Stress Echocardiography.Diagnostics (Basel, Switzerland) · 2025Article
- Validity of resting strain/strain rate in prediction of myocardial viability.The international journal of cardiovascular imaging · 2022Article
- Assessment of myocardial viability using echocardiographic strain imaging in patients with ST-elevation myocardial infarction: comparison with cardiac PET imaging.Journal of echocardiography · 2020Observational
- Comparison between Visual Assessment and Longitudinal Strain during Dobutamine Stress Echocardiography.Journal of cardiovascular echographyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLow-dose dobutamine stress echocardiography is increasingly used for identifying myocardial viability.
aimWe explored whether dobutamine-induced strain (S) and strain rate (SR) can identify myocardial viability following fibrinolytic therapy for ST-segment-elevation myocardial infarction (STEMI), taking (99m)Tc-sestamibi scintigraphy as the "gold standard" for diagnosis.
methodsWe enrolled 60 consecutive patients presenting for myocardial viability assessment at least 4 weeks following STEMI. S and SR were measured by tissue Doppler imaging individually for all myocardial segments under low-dose dobutamine stress echocardiography. Patients underwent resting (99m)Tc-sestamibi scintigraphy using the standard imaging technique. Based on the results of (99m)Tc-sestamibi scintigraphy, the dobutamine-induced S and SR were compared between viable and non-viable segments. Receiver-operating characteristics curve was constructed to determine the cutoff value of the dobutamine-induced S and SR that best identifies viability.
resultsThe dobutamine-induced S and SR were significantly higher in viable compared with non-viable segments, a finding that was consistent for most individual myocardial segments (10 out of 16 for S and 11 out of 16 for SR). A cutoff value ranging from -8.5 to -9.6% for the S identified viability in apical and mid- segments, whereas a cutoff value ranging from -11.5 to -21.5% identified viability in basal segments. Similarly, a cutoff value ranging from -0.5 to -1.2 s(-1) for the SR identified viability in apical and mid-segments, whereas a cutoff value ranging from -1.4 to -1.7/s(-1) identified viability in basal segments.
conclusionIn patients undergoing viability assessment following fibrinolytic therapy for STEMI, the dobutamine-induced S and SR were higher in viable versus non-viable segments. A cutoff value of dobutamine-induced S and SR identified viability in most individual myocardial segments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.