Evidence map›Paper›PMID 26664865›Full record

ReviewFrontiers in cardiovascular medicine2014

Balloon Angioplasty - The Legacy of Andreas Grüntzig, M.D. (1939-1985).

Matthias Barton, Johannes Grüntzig, Marc Husmann, Josef Rösch

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 107 citations in OpenAlex.

  1. Review
  2. Tracing the evolution of cardiology: Pioneering discoveries and paradigm shifts in cardiovascular care.American heart journal plus : cardiology research and practice · 2026
    Review
  3. Review
  4. Coronary Intervention: History and Current Status.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025
    Review
  5. The History of Coronary Artery Disease.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Drug-Coated Balloons for Coronary Interventions: A Focused Review.Methodist DeBakey cardiovascular journal · 2025
    Review
  10. Article
  11. Review
  12. Femoro-popliteal endovascular interventions.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024
    Review
  13. Zero Radiation in the Cardiac Catheterization Laboratory: An Aspirational Goal or Moral Imperative?Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Article
  14. Review
  15. Article
  16. Balloon rupture with eversion during innominate vein angioplasty requiring surgical retrieval.Journal of vascular surgery cases and innovative techniques · 2023
    Article
  17. Review
  18. Stent, balloon and hybrid inThe British journal of cardiology · 2023
    Article
  19. Clinical Outcomes of a Non-Compliant Balloon Dilatation Catheter: MOZEC™ NC Study.International journal of environmental research and public health · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Matthias BartonUniversity of Zürich , Zürich , Switzerland.
Johannes GrüntzigHeinrich Heine-Universität , Düsseldorf , Germany.
Marc HusmannUniversity Hospital Zürich , Zürich , Switzerland.
Josef RöschDotter Interventional Institute, OHSU , Portland, OR , USA.
University of Zurich · CHHeinrich Heine University Düsseldorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 1974, at the Medical Policlinic of the University of Zürich, German-born physician-scientist Andreas Grüntzig (1939-1985) for the first time applied a balloon-tipped catheter to re-open a severely stenosed femoral artery, a procedure, which he initially called "percutaneous transluminal dilatation". Balloon angioplasty as a therapy of atherosclerotic vascular disease, for which Grüntzig and Charles T. Dotter (1920-1985) received a nomination for the Nobel Prize in Physiology or Medicine in 1978, became one of the most successful examples of translational medicine in the twentieth century. Known today as percutaneous transluminal angioplasty (PTA) in peripheral arteries or percutaneous transluminal coronary angioplasty (PTCA) or percutaneous coronary intervention (PCI) in coronary arteries, balloon angioplasty has become the method of choice to treat patients with acute myocardial infarction or occluded leg arteries. On the occasion of the 40(th) anniversary of balloon angioplasty, we summarize Grüntzig's life and career in Germany, Switzerland, and the United States and also review the developments in vascular medicine from the 1890s to the 1980s, including Dotter's first accidental angioplasty in 1963. The work of pioneers of catheterization, including Pedro L. Fariñas in Cuba, André F. Cournand in France, Werner Forssmann, Werner Porstmann and Eberhard Zeitler in Germany, António Egas Moniz and Reynaldo dos Santos in Portugal, Sven-Ivar Seldinger in Sweden, and Barney Brooks, Thomas J. Fogarty, Melvin P. Judkins, Richard K. Myler, Dickinson W. Richards, and F. Mason Sones in the United States, is discussed. We also present quotes by Grüntzig and excerpts from his unfinished autobiography, statements of Grüntzig's former colleagues and contemporary witnesses, and have included hitherto unpublished historic photographs and links to archive recordings and historic materials. This year, on June 25, 2014, Andreas Grüntzig would have celebrated his 75(th) birthday. This article is dedicated to his memory.

Indexed as

Alexis CarrelAndreas Gruentzigatherosclerosisautobiographybiographycoronary artery diseaseNobel Prizeperipheral vascular diseaseRobert Hegglin

Identifiers

PMID26664865
PMCPMC4671350
OpenAlexW2095791911

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.