ArticleJournal of clinical & experimental ophthalmology2015
Primary Open-Angle Glaucoma in Individuals of African Descent: A Review of Risk Factors.
Article in Journal of clinical & experimental ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Minimally invasive trabecular meshwork surgery for open-angle glaucoma.The Cochrane database of systematic reviews · 2026Pooled it
- Novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation.Cell reports. Medicine · 2024Pooled it
- Racial and Ethnic Disparities in Primary Open-Angle Glaucoma Clinical Trials: A Systematic Review and Meta-analysis.JAMA network open · 2021Pooled it
- "I want to see everything": A community-based participatory research framework to identify eye health and vision care knowledge, perceptions, values, and barriers.Journal of clinical and translational science · 2026Article
- Racial and Ethnic Disparities in Prescription of a Novel Agent in Medical Management of Primary Open-Angle Glaucoma.Ophthalmic epidemiology · 2025Article
- Affordable Sinskey Hook Goniotomy and Cataract Surgery in Black and Afro-Latino Patients Diagnosed with Glaucoma: Retrospective Real-World One-Year Results.Journal of clinical medicine · 2025Article
- Article
- Adjunctive use of netarsudil 0.02% in the treatment of refractory glaucoma: a one year analysis.International ophthalmology · 2024Article
- Priorities for health outcomes in glaucoma in an ethnically diverse UK cohort: an observational study.BMJ open · 2024Observational
- Stress, Allostatic Load, and Neuroinflammation: Implications for Racial and Socioeconomic Health Disparities in Glaucoma.International journal of molecular sciences · 2024Review
- Comparison of Corvis ST Parameters between Primary Open-Angle Glaucoma and Primary Angle-Closure Glaucoma.Journal of clinical medicine · 2023Article
- Quality of Life among Patients with Glaucoma in the West Bank, Palestine: A Cross-Sectional Study.Ethiopian journal of health sciences · 2023Article
- Paving the way while playing catch up: mitochondrial genetics in African ancestry primary open-angle glaucoma.Frontiers in ophthalmology · 2023Article
- Article
- Association between vascular comorbidity and glaucoma progression: A four-year observational study.Experimental and therapeutic medicine · 2021Article
- Deep learning in glaucoma with optical coherence tomography: a review.Eye (London, England) · 2021Review
- HEALTH-RELATED QUALITY OF LIFE IN PRIMARY OPEN-ANGLE GLAUCOMA PATIENTS.Acta clinica Croatica · 2020Article
- Combined Multi-Modal Assessment of Glaucomatous Damage With Electroretinography and Optical Coherence Tomography/Angiography.Translational vision science & technology · 2020Article
- Optic Disc and Macular Vessel Density Measured by Optical Coherence Tomography Angiography in Open-Angle and Angle-Closure Glaucoma.Scientific reports · 2020Article
- Visual Impairment and Mental Health: Unmet Needs and Treatment Options.Clinical ophthalmology (Auckland, N.Z.) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo identify the major risk factors for primary open-angle glaucoma (POAG) in individuals of African descent.
methodsWe searched PubMed for relevant articles, with results spanning April 1947 to present. All abstracts were reviewed and, where relevant to POAG and race, articles were catalogued and analyzed. Additional sources were identified through citations in articles returned by our search.
resultsNumerous potential POAG risk factors were identified and organized into categories by demographics (age, sex, and skin color), lifestyle choices (smoking, alcohol), comorbidities (hypertension, diabetes, and obesity), ophthalmic findings (eye structure, central corneal thickness, corneal hysteresis, elevated intraocular pressure, myopia, cataract, and vascular abnormalities), family history, socioeconomic status, and adherence. Older age, male sex, lower central corneal thickness, decreased corneal hysteresis, elevated intraocular pressure, myopia, vascular abnormalities, and positive family history were definitively associated with increased risk of POAG.
conclusionsIndividuals at greatest risk for POAG should be screened by an ophthalmologist to allow earlier detection and to slow disease progression. Further studies on the genetics of the disease will provide more insight into underlying pathologic mechanisms and could lead to improved therapeutic interventions. Continued research in urban areas with large populations of blacks is especially needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.