Evidence map›Paper›PMID 26664630›Full record

ArticleBeilstein journal of organic chemistry2015

Copper-mediated synthesis of N-alkenyl-α,β-unsaturated nitrones and their conversion to tri- and tetrasubstituted pyridines.

Dimitra Kontokosta, Daniel S Mueller, Dong-Liang Mo, Wiktoria H Pace, Rachel A Simpson, Laura L Anderson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Beilstein journal of organic chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dimitra KontokostaDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, U.S.A.
Daniel S MuellerDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, U.S.A.
Dong-Liang MoDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, U.S.A.
Wiktoria H PaceDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, U.S.A.
Rachel A SimpsonDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, U.S.A.
Laura L AndersonDepartment of Chemistry, University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, U.S.A.

Funding

Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
NCATS NIH HHS UL1 TR000430
6 · The paper itself

Abstract

A Chan-Lam reaction has been used to prepare N-alkenyl-α,β-unsaturated nitrones, which undergo a subsequent thermal rearrangement to the corresponding tri- and tetrasubstituted pyridines. The optimization and scope of these transformations is discussed. Initial mechanistic experiments suggest a reaction pathway involving oxygen transfer followed by cyclization.

Indexed as

Chan–Lamcoppernitroneoxygen transferpyridine

Identifiers

PMID26664630
PMCPMC4660996

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.