Evidence map›Paper›PMID 26664448›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2015

Topical Anti-Inflammatory Activity of Oil from Tropidurus hispidus (Spix, 1825).

Israel J M Santos, Gerlânia O Leite, José Galberto M Costa, Romulo R N Alves, Adriana R Campos, Irwin R A Menezes, Francisco Ronaldo V Freita, Maria Janeth H Nunes, Waltécio O Almeida

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Use of Natural Products in Asthma Treatment.Evidence-based complementary and alternative medicine : eCAM · 2020
    Review
  3. Article
  4. BIOLOGICAL AND PHYTOCHEMICAL INVESTIGATIONS OF EXTRACTS FROMAfrican journal of traditional, complementary, and alternative medicines : AJTCAM · 2017
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Israel J M SantosLaboratory of Zoology, Regional University of Cariri (URCA), Pimenta, 63105-000 Crato, CE, Brazil.
Gerlânia O LeiteProgram of Post-Graduation in Pharmacology, Federal University of Santa Maria, Campus Camobi, 97105-900 Santa Maria, RS, Brazil.
José Galberto M CostaLaboratory of Natural Products Research, Regional University of Cariri (URCA), Pimenta, 63105-000 Crato, CE, Brazil.
Romulo R N AlvesDepartment of Biology, Paraiba State University (UEPB), 58429-500 João Pessoa, PB, Brazil ; Programa de Pós Graduação em Etnobiologia e Conservação da Natureza, Departamento de Ciências Biológicas, Universidade Federal Rural de Pernambuco, Rua Dom Manoel de Medeiros s/n, Dois Irmãos, 52171-900 Recife, PE, Brazil.
Adriana R CamposUniversidade de Fortaleza, Avenida Washington Soares 1321, 60811-905 Fortaleza, CE, Brazil.
Irwin R A MenezesLaboratory of Pharmacology and Medicinal Chemistry, Regional University of Cariri (URCA), Pimenta, 63105-000 Crato, CE, Brazil.
Francisco Ronaldo V FreitaLaboratory of Carcinology, Regional University of Cariri (URCA), Pimenta, 63105-000 Crato, CE, Brazil.
Maria Janeth H NunesDepartment of Nursing, Regional University of Cariri, 63105-000 Crato, CE, Brazil.
Waltécio O AlmeidaLaboratory of Zoology, Regional University of Cariri (URCA), Pimenta, 63105-000 Crato, CE, Brazil.
Universidade Regional do Cariri · BRUniversidade de Fortaleza · BRUniversidade Federal de Santa Maria · BRUniversidade Federal Rural de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tropidurus hispidus has been used in traditional medicine in several regions of Northeastern Region of Brazil. Its medicinal use involves the treatment of diseases such as warts, sore throat, tonsillitis, chicken pox, varicella, measles, asthma, alcoholism, and dermatomycosis. The present study evaluated the topical anti-inflammatory activity of Tropidurus hispidus fat in treating ear edema in an animal model. Oil from T. hispidus (OTH) was evaluated on its effect against experimental inflammation in mice. OTH was extracted from body fat located in the ventral region of Tropidurus hispidus using hexane as a solvent. We used the model of mouse ear edema induced by phlogistic agents, croton oil (single and multiple applications), arachidonic acid, phenol, capsaicin, and histamine, applied into the right ears of animals pretreated with acetone (control), dexamethasone, or OTH. OTH inhibited the dermatitis induced by all noxious agents, except capsaicin. This effect may be related to the fatty acids present in OTH.

Identifiers

PMID26664448
PMCPMC4667054
OpenAlexW2176160570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.