Evidence map›Paper›PMID 26664413›Full record

ArticleJournal of tropical medicine2015

Leukogram Profile and Clinical Status in vivax and falciparum Malaria Patients from Colombia.

Alberto Tobón-Castaño, Esteban Mesa-Echeverry, Andrés Felipe Miranda-Arboleda

Open access · goldAbstract read
In one paragraph

Article in Journal of tropical medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Health science reports · 2026
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  3. Naturally acquired antibodies toFrontiers in immunology · 2026
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  9. Epidemiological characteristics ofFrontiers in cellular and infection microbiology · 2022
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  13. A comparative study assessing the effect of haematological and biochemical parameters on the pathogenesis of malaria.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2019
    Article
  14. Article
  15. Article
  16. New laboratory perspectives for evaluation of vivax malaria infected patients: a useful tool for infection monitoring.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alberto Tobón-CastañoGrupo Malaria, Facultad de Medicina, Universidad de Antioquia, Calle 70, No. 52-21, Medellín, Colombia.
Esteban Mesa-EcheverryGrupo Malaria, Facultad de Medicina, Universidad de Antioquia, Calle 70, No. 52-21, Medellín, Colombia.
Andrés Felipe Miranda-ArboledaGrupo Malaria, Facultad de Medicina, Universidad de Antioquia, Calle 70, No. 52-21, Medellín, Colombia.
Universidad de Antioquia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction. Hematological alterations are frequent in malaria patients; the relationship between alterations in white blood cell counts and clinical status in malaria is not well understood. In Colombia, with low endemicity and unstable transmission for malaria, with malaria vivax predominance, the hematologic profile in malaria patients is not well characterized. The aim of this study was to characterize the leukogram in malaria patients and to analyze its alterations in relation to the clinical status. Methods. 888 leukogram profiles of malaria patients from different Colombian regions were studied: 556 with P. falciparum infection (62.6%), 313 with P. vivax infection (35.2%), and 19 with mixed infection by these species (2.1%). Results. Leukocyte counts at diagnosis were within normal range in 79% of patients and 18% had leucopenia; the most frequent alteration was lymphopenia (54%) followed by monocytosis (11%); the differential granulocyte count in 298 patients revealed eosinophilia (15%) and high basophil counts (8%). Leukocytosis, eosinopenia, and neutrophilia were associated with clinical complications. The utility of changes in leukocyte counts as markers of severity should be explored in depth. A better understanding of these hematological parameters will allow their use in prompt diagnosis of malaria complications and monitoring treatment response.

Identifiers

PMID26664413
PMCPMC4667023
OpenAlexW2196143462

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.