ArticleInternational journal of MS care
Fatigue, Sleep Quality, and Disability in Relation to Quality of Life in Multiple Sclerosis.
Article in International journal of MS care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Pooled it
- Subjective sleep disturbances are associated with reduced MRI-derived perivascular-space diffusivity in multiple sclerosis.Journal of neurology · 2026Article
- Impact of Depression, Fatigue, and Pain on Quality of Life in Slovak Multiple Sclerosis Patients.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- The Potential of Transcranial Direct Current Stimulation (tDCS) in Improving Quality of Life in Patients with Multiple Sclerosis: A Review and Discussion of Mechanisms of Action.Journal of clinical medicine · 2025Review
- Frequency and risk factors of sleep problems in Egyptian patients with multiple sclerosis.Frontiers in neurology · 2025Article
- The effectiveness of health-related quality of life (HRQOL) model in people with HIV: A cross sectional study.Health science reports · 2024Article
- Exploring humanistic burden of fatigue in adults with multiple sclerosis: an analysis of US National Health and Wellness Survey data.BMC neurology · 2024Article
- The impact of fatigue on people with multiple sclerosis in Morocco.African journal of disability · 2024Article
- Challenges of patients with multiple sclerosis in receiving health care services in Iran.Current journal of neurology · 2023Article
- Remote Testing Apps for Multiple Sclerosis Patients: Scoping Review of Published Articles and Systematic Search and Review of Public Smartphone Apps.JMIR neurotechnology · 2023Review
- Determinants of health-related quality of life in recently detoxified patients with severe alcohol use disorder.Health and quality of life outcomes · 2022Article
- Barriers to quality of life in patients with multiple sclerosis: a qualitative study.BMC neurology · 2022Article
- Prevalence of self-reported fatigue in intensive care unit survivors 6 months-5 years after discharge.Scientific reports · 2022Article
- Sleep Disturbances, Degree of Disability and the Quality of Life in Multiple Sclerosis Patients.International journal of environmental research and public health · 2022Article
- Article
- Signal Detection Theory as a Novel Tool to Understand Cognitive Fatigue in Individuals With Multiple Sclerosis.Frontiers in behavioral neuroscience · 2022Article
- Fatigue, Physical Disability and Self-Efficacy as Predictors of the Acceptance of Illness and Health-Related Quality of Life in Patients with Multiple Sclerosis.International journal of environmental research and public health · 2021Article
- Health-related Quality of Life of People with Multiple Sclerosis in Oman.Oman medical journal · 2021Article
- Symptom clusters and quality of life in persons with multiple sclerosis across the lifespan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Association between sleep quality and domains of quality of life amongst patients with first episode psychosis.Health and quality of life outcomes · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundQuality of life (QOL) is impaired in multiple sclerosis (MS) in part due to physical disability. MS-associated fatigue and poor sleep are common and treatable features of MS that affect QOL. We assessed the association between fatigue, sleep quality, and QOL in people with MS.
methodsCross-sectional data were collected from 217 patients with MS. Health-related QOL (MS Quality of Life-54), fatigue (Fatigue Severity Scale [FSS]), and sleep quality (Pittsburgh Sleep Quality Inventory [PSQI]) were assessed. Expanded Disability Status Scale scores were also provided by a qualified neurologist.
resultsThe mean ± SD age of the 217 patients was 32.6 ± 8.6 years, and 79% were female. One hundred fifty-two patients (70.0%) were classified as poor sleepers based on PSQI scores; 122 (56.2%) had significant fatigue based on FSS results. The mean ± SE physical (PCS) and mental (MCS) health composite scores of the MSQOL-54 were 40.12 ± 1.27 and 43.81 ± 1.61, respectively. There was a strong statistically significant positive correlation between PCS scores and MCS (r = 0.58), FSS (r = 0.49), and PSQI (r = 0.52) scores. MCS scores were strongly correlated with FSS (r = 0.53) and PSQI (r = 0.35) scores. Age exhibited statistically significant negative correlations with PCS (r = -0.21) and MCS (r = -0.58) scores, and was statistically significantly correlated with FSS (r = 0.23) and PSQI (r = 0.21) scores. Expanded Disability Status Scale scores were strongly correlated with FSS scores.
conclusionsThese findings support screening of fatigue severity and sleep quality and their effects on QOL.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.