Evidence map›Paper›PMID 26664156›Full record

ArticleJournal of pain research2015

Approach to the pharmacological management of chronic pain in patients with an alcohol use disorder.

Laura Murphy, Karen Wk Ng, Victoria Ch Su, Sarah Woodworth-Giroux, Todd S Levy, Beth A Sproule, Andrea D Furlan

Abstract read
In one paragraph

Article in Journal of pain research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laura MurphyUniversity Health Network, Toronto, ON, Canada ; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.
Karen Wk NgUniversity Health Network, Toronto, ON, Canada.
Victoria Ch SuSt Paul's Hospital, Lower Mainland Pharmacy Services, Vancouver, BC, Canada.
Sarah Woodworth-GirouxWindsor Regional Hospital, Windsor, ON, Canada.
Todd S LevyUniversity Health Network, Toronto, ON, Canada.
Beth A SprouleLeslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada ; Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.
Andrea D FurlanUniversity Health Network, Toronto, ON, Canada ; Institute for Work and Health, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper provides an overview of research, guidelines, and clinical considerations for the use of medications for chronic pain in the management of patients with an alcohol use disorder. A review of the literature identified randomized controlled trials, epidemiological cohort studies, consensus guidelines, and one systematic review and meta-analysis. Where gaps in the literature existed, clinical experience of the authors is included. Use of nonopioid medications should be given priority and may offer a more favorable risk profile as well as benefits beyond pain management, such as improvement in anxiety, depression, or insomnia. Pregabalin and gabapentin have additional benefits to decrease alcohol cravings or time to relapse after a period of abstinence from alcohol. Drug interactions between selected analgesics and alcohol, disulfiram, or naltrexone require careful consideration.

Indexed as

alcohol use disorderchronic painopioids

Identifiers

PMID26664156
PMCPMC4670016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.