Evidence map›Paper›PMID 26664130›Full record

ReviewVascular health and risk management2015

Personalized medicine and stroke prevention: where are we?

Joosup Kim, Amanda G Thrift, Mark R Nelson, Christopher F Bladin, Dominique A Cadilhac

Open access · goldAbstract readReview
In one paragraph

Review in Vascular health and risk management, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Biomarker Application for Precision Medicine in Stroke.Translational stroke research · 2020
    Review
  8. The clinical practice of risk reduction for Alzheimer's disease: A precision medicine approach.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2018
    Observational
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Joosup KimStroke and Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia ; Public Health, Stroke Division, Florey Institute of Neuroscience and Mental Health, Heidelberg, VIC, Australia.
Amanda G ThriftStroke and Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.
Mark R NelsonDiscipline of General Practice, School of Medicine, Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia.
Christopher F BladinPublic Health, Stroke Division, Florey Institute of Neuroscience and Mental Health, Heidelberg, VIC, Australia ; Eastern Health Clinical School, Monash University, Clayton, VIC, Australia.
Dominique A CadilhacStroke and Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia ; Public Health, Stroke Division, Florey Institute of Neuroscience and Mental Health, Heidelberg, VIC, Australia.
Florey Institute of Neuroscience and Mental Health · AUMonash University · AUUniversity of Tasmania · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are many recommended pharmacological and non-pharmacological therapies for the prevention of stroke, and an ongoing challenge is to improve their uptake. Personalized medicine is seen as a possible solution to this challenge. Although the use of genetic information to guide health care could be considered as the apex of personalized medicine, genetics is not yet routinely used to guide prevention of stroke. Currently personalized aspects of prevention of stroke include tailoring interventions based on global risk, the utilization of individualized management plans within a model of organized care, and patient education. In this review we discuss the progress made in these aspects of prevention of stroke and present a case study to illustrate the issues faced by health care providers and patients with stroke that could be overcome with a personalized approach to the prevention of stroke.

Indexed as

Precision MedicineGenetic MarkersGenetic Predisposition to DiseaseHealth Knowledge, Attitudes, PracticeHumansPatient CompliancePatient Education as TopicPhenotypePrimary PreventionRisk AssessmentRisk FactorsRisk Reduction BehaviorSecondary PreventionStrokeGenetic Markerseducationpersonalized health carepreventionstroke

Identifiers

PMID26664130
PMCPMC4671759
OpenAlexW2182322409

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.