ArticleInternational journal of nanomedicine2015
Green synthesis of silver nanoparticles using cranberry powder aqueous extract: characterization and antimicrobial properties.
Article in International journal of nanomedicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 81 citations in OpenAlex.
- Rifabutin Loaded Biogenic Silver Nanoparticles: Development, Characterization, and Evaluation of Antidiabetic Activity in Streptozotocin Induced Diabetic Rats.Chemistry & biodiversity · 2026Article
- Unlocking the Therapeutic Efficacies of Silver Nanoparticles Derived Using the Plant-Based Aqueous Extract: A Comprehensive Review.Applied biochemistry and biotechnology · 2026Review
- Cranberry: A Promising Natural Product for Animal Health and Performance.Current issues in molecular biology · 2025Review
- Advancing Nanomedicine: For Bone Defect Repair and Regeneration.International journal of nanomedicine · 2025Review
- New approaches of green silver nanoparticles for cancer and biomedical applications: a review.Exploration of targeted anti-tumor therapy · 2025Review
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- Green synthesis of silver nanoparticles fromHeliyon · 2024Article
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- Biofabrication of Nanosilver FromInternational journal of food science · 2024Article
- Evaluating Antioxidant Performance, Biosafety, and Antimicrobial Efficacy ofAntioxidants (Basel, Switzerland) · 2023Article
- Elaboration of Nanostructured Levan-Based Colloid System as a Biological Alternative with Antimicrobial Activity for Applications in the Management of Pathogenic Microorganisms.Nanomaterials (Basel, Switzerland) · 2023Article
- Phytochemical-Based Nanomaterials against Antibiotic-Resistant Bacteria: An Updated Review.Polymers · 2023Review
- Chitosan Surface-Modified PLGA Nanoparticles Loaded with Cranberry Powder Extract as a Potential Oral Delivery Platform for Targeting Colon Cancer Cells.Pharmaceutics · 2023Article
- Pullulan-based films impregnated with silver nanoparticles from theFrontiers in bioengineering and biotechnology · 2023Article
- Biomedical Applications of Plant Extract-Synthesized Silver Nanoparticles.Biomedicines · 2022Review
- Comparative Cytotoxic Evaluation ofPharmaceuticals (Basel, Switzerland) · 2022Article
- Comparative Estimation of the Cytotoxic Activity of Different Parts ofPharmaceutics · 2022Article
- Silver Nanoparticles Formulation of Flower Head's Polyphenols ofMolecules (Basel, Switzerland) · 2022Article
- Green Synthesis of Silver Nanoparticles Using the Plant Extract ofMolecules (Basel, Switzerland) · 2022Article
- A Critical Review of the Antimicrobial and Antibiofilm Activities of Green-Synthesized Plant-Based Metallic Nanoparticles.Nanomaterials (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe growing threat of microbial resistance against traditional antibiotics has prompted the development of several antimicrobial nanoparticles (NPs), including silver NPs (AgNPs). In this article, a simple and eco-friendly method for the synthesis of AgNPs using the cranberry powder aqueous extract is reported. MATERIALS AND
methodsCranberry powder aqueous extracts (0.2%, 0.5%, and 0.8% w/v) were allowed to interact for 24 hours with a silver nitrate solution (10 mM) at 30°C at a ratio of 1:10. The formation of AgNPs was confirmed by ultraviolet-visible spectroscopy and their concentrations were determined using atomic absorption spectroscopy. The prepared NPs were evaluated by transmission electron microscopy, measurement of ζ-potential, and Fourier-transform infrared spectroscopy. The in vitro antimicrobial properties of AgNPs were then investigated against several microbial strains. Finally, in vivo appraisal of both wound-healing and antimicrobial properties of either plain AgNPs (prepared using 0.2% extract) or AgNP-Pluronic F-127 gel was conducted in a rat model after induction of a Staphylococcus aureus ATCC 6538P wound infection.
resultsThe formation of AgNPs was confirmed by ultraviolet-visible spectroscopy, where a surface-plasmon resonance absorption peak was observed between 432 and 438 nm. Both size and concentration of the formed AgNPs increased with increasing concentration of the extracts. The developed NPs were stable, almost spherical, and polydisperse, with a size range of 1.4-8.6 nm. The negative ζ-potential values, as well as Fourier-transform infrared spectroscopy analysis, indicated the presence of a capping agent adsorbed onto the surface of the particles. In vitro antimicrobial evaluation revealed a size-dependent activity of the AgNPs against the tested organisms. Finally, AgNPs prepared using 0.2% extract exhibited a substantial in vivo healing potential for full-thickness excision wounds in rats.
conclusionAgNPs were successfully synthesized from a silver nitrate solution through a simple green route, using cranberry powder aqueous extract as a reducing as well as capping agent.
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