Evidence map›Paper›PMID 26663866›Full record

Observational studyJournal of clinical hypertension (Greenwich, Conn.)2016

Cardiorespiratory Fitness Suppresses Age-Related Arterial Stiffening in Healthy Adults: A 2-Year Longitudinal Observational Study.

Yuko Gando, Haruka Murakami, Ryoko Kawakami, Kenta Yamamoto, Hiroshi Kawano, Noriko Tanaka, Susumu S Sawada, Nobuyuki Miyatake, Motohiko Miyachi

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of clinical hypertension (Greenwich, Conn.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  14. Fitness: The "Secret" of Vascular Youth.Journal of clinical hypertension (Greenwich, Conn.) · 2016
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Yuko GandoDepartment of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.
Haruka MurakamiDepartment of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.
Ryoko KawakamiDepartment of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.
Kenta YamamotoDepartment of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.
Hiroshi KawanoDepartment of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.
Noriko TanakaDepartment of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.
Susumu S SawadaDepartment of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.
Nobuyuki MiyatakeDepartment of Hygiene, Faculty of Medicine, Kagawa University, Miki, Kagawa, Japan.
Motohiko MiyachiDepartment of Health Promotion and Exercise, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiorespiratory fitness is negatively associated with arterial stiffness, although it is unclear whether it is associated with prospective arterial stiffness changes. The authors examined cardiorespiratory fitness and arterial stiffness progression in a 2-year follow-up study of 470 healthy men and women aged 26 to 69 years. Peak oxygen uptake (V˙O2peak) was measured at baseline using a graded cycle exercise test. Arterial stiffness was assessed using brachial-ankle pulse wave velocity (baPWV) at baseline and after 2 years. Two-year changes in baPWV were significantly higher in patients in the lowest V˙O2peak tertile (28.8±7.6 cm/s) compared with those in the highest V˙O2peak tertile (-1.4±7.5 cm/s) (P=.024) and were inversely correlated with V˙O2peak (r=-.112, P=.015). Stepwise multiple regression analysis revealed that age, glucose, baPWV, V˙O2peak, and sex were independent correlates of 2-year changes in baPWV, suggesting that higher cardiorespiratory fitness is associated with age-related arterial stiffening suppression.

Indexed as

AdultAgedAged, 80 and overAgingAnkle Brachial IndexBlood PressureBrachial ArteryCardiorespiratory FitnessDisease ProgressionExercise TestFemaleFollow-Up StudiesHealthy VolunteersHumansHypertensionMale

Identifiers

PMID26663866
PMCPMC8031982

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.