ArticlePediatric obesity2016
Exploring the association between maternal prenatal multivitamin use and early infant growth: The Healthy Start Study.
Article in Pediatric obesity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- Prenatal exposure to tobacco and adverse birth outcomes: effect modification by folate intake during pregnancy.Maternal health, neonatology and perinatology · 2022Article
- Developmental origins of metabolic diseases.Physiological reviews · 2021Review
- Determinants of Infant Adiposity across the First 6 Months of Life: Evidence from the Baby-bod study.Journal of clinical medicine · 2021Article
- Incidence and timing of offspring asthma, wheeze, allergic rhinitis, atopic dermatitis, and food allergy and association with maternal history of asthma and allergic rhinitis.The World Allergy Organization journal · 2021Article
- Observational
- Distribution and predictors of urinary concentrations of phthalate metabolites and phenols among pregnant women in the Healthy Start Study.Environmental research · 2018Article
- An observational cohort study of weight- and length-derived anthropometric indicators with body composition at birth and 5 mo: the Healthy Start study.The American journal of clinical nutrition · 2017Observational
- Prenatal Vitamin D Intake, Cord Blood 25-Hydroxyvitamin D, and Offspring Body Composition: The Healthy Start Study.Nutrients · 2017Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPrenatal multivitamin supplementation is recommended to improve offspring outcomes, but effects on early infant growth are unknown.
objectivesWe examined whether multivitamin supplementation in the year before delivery predicts offspring mass, body composition and early infant growth.
methodsMultivitamin use was assessed longitudinally in 626 women from the Healthy Start Study. Offspring body size and composition was measured with air displacement plethysmography at birth (<3 days) and postnatally (median 5.2 months). Separate multiple linear regressions assessed the relationship of weeks of daily multivitamin use with offspring mass, body composition and postnatal growth, after adjustment for potential confounders (maternal age, race, pre-pregnant body mass index; offspring gestational age at birth, sex; breastfeeding exclusivity).
resultsMaternal multivitamin use was not related to offspring mass or body composition at birth, or rate of change in total or fat-free mass in the first 5 months. Multivitamin use was inversely associated with average monthly growth in offspring percent fat mass (β = -0.009, p = 0.049) between birth and postnatal exam. Offspring of non-users had a monthly increase in percent fat mass of 3.45%, while offspring at the top quartile of multivitamin users had a monthly increase in percent fat mass of 3.06%. This association was not modified by exclusive breastfeeding.
conclusionsIncreased multivitamin use in the pre-conception and prenatal periods was associated with a slower rate of growth in offspring percent fat mass in the first 5 months of life. This study provides further evidence that in utero nutrient exposures may affect offspring adiposity beyond birth.
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