Evidence map›Paper›PMID 26663505›Full record

ArticleClinical and translational science2015

Incorporating Informatics for Integrating Biology and the Bedside (i2b2) into Predoctoral Trainee Curriculum to Evaluate Student-Generated Hypotheses.

Kathleen M Schieffer, Douglas G Peters, Chesney K Richter, Welley S Loc, James A Pawelczyk

Abstract read
In one paragraph

Article in Clinical and translational science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kathleen M SchiefferTL1 Training Program, Penn State Clinical and Translational Sciences Institute, Hershey, Pennsylvania, USA.
Douglas G PetersTL1 Training Program, Penn State Clinical and Translational Sciences Institute, Hershey, Pennsylvania, USA.
Chesney K RichterTL1 Training Program, Penn State Clinical and Translational Sciences Institute, Hershey, Pennsylvania, USA.
Welley S LocTL1 Training Program, Penn State Clinical and Translational Sciences Institute, Hershey, Pennsylvania, USA.
James A PawelczykNoll Laboratory, Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, USA.

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
Penn State Clinical and Translational Science InstituteKL2TR000126 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$3.2M
Penn State Clinical and Translational Science InstituteTL1TR000125 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$550k
NCATS NIH HHS KL2 TR000126NCATS NIH HHS TL1 TR000125NCATS NIH HHS UL1 TR000127NCATS NIH HHS UL1 TR002014
6 · The paper itself

Abstract

As part of the Clinical and Translational Science Institute predoctoral TL1 training program at the Pennsylvania State University, a multidisciplinary team of predoctoral trainees representing the Chemistry, Neurosurgery, Nutritional Sciences, and Public Health Sciences departments were introduced to the NIH-sponsored Informatics for Integrating Biology and the Bedside (i2b2) database to test the following student-generated hypothesis: children with iron deficiency anemia (IDA) are at increased risk of attention deficit-hyperactivity disorder (ADHD). Children aged 4-12 and 4-17 years were categorized into IDA and control groups. De-identified medical records from the Penn State Milton S. Hershey Medical Center (HMC) and the Virginia Commonwealth University Medical Center (VCUMC) were used for the analysis. Overall, ADHD prevalence at each institution was lower than 2011 state estimates. There was a significant association between IDA and ADHD in the 4-17-year-old age group for all children (OR: 1.902 [95% CI: 1.363-2.656]), Caucasian children (OR: 1.802 [95% CI: 1.133-2.864]), and African American children (OR: 1.865 [95% CI: 1.152-3.021]). Clinical and Translational Science Award (CTSA) infrastructure is particularly useful for trainees to answer de novo scientific questions with minimal additional training and technical expertise. Moreover, projects can be expanded by collaborating within the CTSA network.

Indexed as

CurriculumAdolescentAnemia, Iron-DeficiencyAttention Deficit Disorder with HyperactivityChildChild, PreschoolElectronic Health RecordsFemaleHumansMaleMedical InformaticsNational Institutes of Health (U.S.)PennsylvaniaPrevalenceResearch DesignSEER Programanemia-nutritionalattention-deficit/hyperactivity disorderbioinformaticscobalaminfolate < anemiaironmedical recordspredoctoral

Identifiers

PMID26663505
PMCPMC4703454

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.