ReviewActa paediatrica (Oslo, Norway : 1992)2016
The neuroscience and context of adolescent depression.
Review in Acta paediatrica (Oslo, Norway : 1992), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Psychiatric comorbidities in children and adolescents with chronic urticaria.World journal of pediatrics : WJP · 2023Pooled it
- Examining the Effectiveness of a Web-Based Intervention for Depressive Symptoms in Female Adolescents: Applying Social Cognitive Theory.Journal of research in health sciences · 2019Trial
- Transcranial Magnetic Stimulation Markers of Antidepressant Treatment in Adolescents With Major Depressive Disorder.The international journal of neuropsychopharmacology · 2019Trial
- High-definition tDCS regulate the prefrontal-limbic-striatal connectivity and reduce depression in youth with first-episode depression.BMC psychiatry · 2026Article
- The impact of family and peer relationships on developmental trajectories of depressive and anxiety symptoms among young people: a person-oriented approach.Child and adolescent psychiatry and mental health · 2026Article
- The association between physical activity and depressive symptoms in adolescents: the serial mediating roles of school connectedness and self-control.Frontiers in public health · 2026Article
- Cortical high-threshold and low-activation characteristics in adolescent depression: a cross-age differential analysis.Frontiers in psychiatry · 2026Article
- Pharmacovigilance of SSRIs in Children and Adolescents with Depression: Disproportionality Analysis of Serotonin Adverse Events Using the FAERS Database.Current medicinal chemistry · 2026Article
- Article
- Clinical effectiveness of training for awareness, resilience, and action for adolescents and young adults with depression: The pilot phase of a multicenter randomized controlled trial.Frontiers in psychiatry · 2023Article
- Preventive strategies for adolescent depression: What are we missing? A focus on biomarkers.Brain, behavior, & immunity - health · 2021Article
- Multimodal assessment of sustained threat in adolescents with nonsuicidal self-injury.Development and psychopathology · 2021Article
- Linking RDoC and HiTOP: A new interface for advancing psychiatric nosology and neuroscience.Clinical psychology review · 2021Review
- Exposure to Criticism Modulates Left but Not Right Amygdala Functional Connectivity in Healthy Adolescents: Individual Influences of Perceived and Self-Criticism.Frontiers in psychiatry · 2021Article
- Hair cortisol and depressive symptoms in youth: An investigation of curvilinear relationships.Psychoneuroendocrinology · 2019Article
- What Role Does the Prefrontal Cortex Play in the Processing of Negative and Positive Stimuli in Adolescent Depression?Brain sciences · 2019Article
- Transcranial Direct Current Stimulation: Considerations for Research in Adolescent Depression.Frontiers in psychiatry · 2017Review
- Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: "Training for Awareness Resilience and Action" (TARA)-A Pilot Study.Frontiers in psychiatry · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
unlabelledAdolescent depression is a growing public health concern with an increased risk of negative health outcomes, including suicide. The use of antidepressants and psychotherapy has not halted its increasing prevalence, and there is a critical need for effective prevention and treatment. We reviewed the neuroscience of adolescent depression, with a focus on the neurocircuitry of sustained threat and summarised contextual factors that have an impact on brain development and the pathophysiology of depression. We also reviewed novel treatment models.
conclusionAttention to the relevant neurocircuitry and contextual factors implicated in adolescent depression is necessary to advance prevention and treatment development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.