Evidence map›Paper›PMID 26663189›Full record

ArticleAdvances in experimental medicine and biology2015

microRNA and Wound Healing.

Jaideep Banerjee, Chandan K Sen

Open access · greenAbstract read
In one paragraph

Article in Advances in experimental medicine and biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Outcomes following spinal instrumented fusions in patients with parkinson's disease: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Pooled it
  2. A Clue on the Skin: A Systematic Review on Immunohistochemical Analyses of the Ligature Mark.International journal of environmental research and public health · 2022
    Pooled it
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  8. Bioactive materials forBioactive materials · 2024
    Review
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  17. Chronic wounds.Nature reviews. Disease primers · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jaideep BanerjeeExtremity Trauma and Regenerative Medicine Division, US Army Institute of Surgical Research, 3698 Chambers Pass, BHT-1, Joint Base-San Antonio, Fort Sam Houston, San Antonio, TX, 78234, USA. jaideep.b@gmail.com.
Chandan K SenThe Ohio State University Wexner Medical Center, Davis Heart & Lung Research Institute, Comprehensive Wound Center, Center for Regenerative Medicine & Cell-Based Therapies, 473 West, 12th Avenue, Columbus, OH, 43210, USA. Chandan.Sen@osumc.edu.
Joint Base San Antonio · USThe Ohio State University Wexner Medical Center · US

Funding

Redox Control of Wound HealingR01GM069589 · NIGMS · OHIO STATE UNIVERSITY · PI SEN, CHANDAN K · 2004 to 2013
$2.3M
Tissue Oxygenation and Wound HealingR01GM077185 · NIGMS · OHIO STATE UNIVERSITY · PI SEN, CHANDAN K · 2007 to 2016
$2.3M
Biofilms and Immunity in Chronic WoundsR01NR013898 · NINR · OHIO STATE UNIVERSITY · PI SEN, CHANDAN K, WOZNIAK, DANIEL J · 2012 to 2016
$2.1M
Mechanisms underlying impaired diabetic wound healingR01DK076566 · NIDDK · OHIO STATE UNIVERSITY · PI ROY, SASHWATI · 2008 to 2011
$1.2M
Novel Regulators of Wound AngiogenesisR01GM108014 · NIGMS · OHIO STATE UNIVERSITY · PI SEN, CHANDAN K · 2015 to 2018
$1.2M
Mechanisms underlying impaired diabetic wound healingR56DK076566 · NIDDK · OHIO STATE UNIVERSITY · PI ROY, SASHWATI · 2016 to 2016
$347k
NIDDK NIH HHS DK076566NIDDK NIH HHS R01 DK076566NIDDK NIH HHS R56 DK076566NIGMS NIH HHS R01 GM069589NIGMS NIH HHS R01 GM077185NIGMS NIH HHS R01 GM108014NINR NIH HHS NR013898NINR NIH HHS R01 NR013898
6 · The paper itself

Abstract

microRNAs (miRNAs) are small noncoding RNA molecules which play pivotal roles in wound healing. The increased expression of certain genes and expression of some others represent a key component of the wound biology and are largely under the regulation of naturally occurring miRNAs. Understanding the dysregulated miRNAs in chronic wound biology will therefore enable the development of newer therapies. This chapter focuses on the miRNAs that can be potentially targeted for improving skin wound healing and the challenges in miRNA therapy, including considerations in miRNA target identification and delivery.

Indexed as

Gene Expression RegulationAnimalsHumansHypoxiaHypoxia-Inducible Factor 1, alpha SubunitMicroRNAsModels, GeneticNeovascularization, PhysiologicRe-EpithelializationSkinSkin DiseasesWound HealingHypoxia-Inducible Factor 1, alpha SubunitMicroRNAsAngiogenesisHypoxymiRsInflammationRe-epithelializationWound healing

Identifiers

PMID26663189
PMCPMC5096456
OpenAlexW2200940546

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.