Evidence map›Paper›PMID 26662983›Full record

ArticleAdvances in experimental medicine and biology2015

A Fleeting Glimpse Inside microRNA, Epigenetics, and Micropeptidomics.

Gaetano Santulli

Abstract read
In one paragraph

Article in Advances in experimental medicine and biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. MicroRNAs and Endothelial (Dys) Function.Journal of cellular physiology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gaetano SantulliColumbia University Medical Center, New York, NY, USA. gsantulli001@gmail.com.

Funding

Targeting intracellular calcium leak as novel therapy for diabetesK99DK107895 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SANTULLI, GAETANO · 2015 to 2016
$176k
American Heart Association-American Stroke Association 15SDG25300007NIDDK NIH HHS K99 DK107895NIDDK NIH HHS K99DK107895
6 · The paper itself

Abstract

MicroRNAs (miRs) are important regulators of gene expression in numerous biological processes. Their maturation process is herein described, including the most updated insights from the current literature. Circa 2000 miR sequences have been identified in the human genome, with over 50,000 miR-target interactions, including enzymes involved in epigenetic modulation of gene expression. Moreover, some "pieces of RNA" previously annotated as noncoding have been recently found to encode micropeptides that carry out critical mechanistic functions in the cell. Advanced techniques now available will certainly allow a precise scanning of the genome looking for micropeptides hidden within the "noncoding" RNA.

Indexed as

Epigenesis, GeneticAnimalsGenomeGenomicsHumansMicroRNAsPeptidesMicroRNAsPeptidesDicerDroshaEpimiRExportinHumaninMETTL3MicropeptidesMicropeptidomeMicropeptidomicsmiRBasemiRNAmiRWalkMitochondriaMOTS-cMyogeninORFPharmacogenomicsPrecision medicineRISCSERCATargetScanTranscriptome

Identifiers

PMID26662983
PMCPMC4871246

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.