Evidence map›Paper›PMID 26662925›Full record

ArticleArchives of disease in childhood2016

Characteristics of admissions and variations in the use of basic investigations, treatments and outcomes in Kenyan hospitals within a new Clinical Information Network.

Philip Ayieko, Morris Ogero, Boniface Makone, Thomas Julius, George Mbevi, Wycliffe Nyachiro, Rachel Nyamai, Fred Were, David Githanga, Grace Irimu and 2 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Archives of disease in childhood, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
13.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Philip AyiekoKenya Medical Research Institute/Wellcome Trust Research Programme, Nairobi, Kenya.
Morris OgeroKenya Medical Research Institute/Wellcome Trust Research Programme, Nairobi, Kenya.
Boniface MakoneKenya Medical Research Institute/Wellcome Trust Research Programme, Nairobi, Kenya.
Thomas JuliusKenya Medical Research Institute/Wellcome Trust Research Programme, Nairobi, Kenya.
George MbeviKenya Medical Research Institute/Wellcome Trust Research Programme, Nairobi, Kenya.
Wycliffe NyachiroKenya Medical Research Institute/Wellcome Trust Research Programme, Nairobi, Kenya.
Rachel NyamaiDivision of Maternal, Newborn, Child and Adolescent Health, Ministry of Health, Nairobi, Kenya.
Fred WereSchool of Medicine, University of Nairobi, Nairobi, Kenya.
David GithangaKenya Paediatric Association, Nairobi, Kenya.
Grace IrimuKenya Medical Research Institute/Wellcome Trust Research Programme, Nairobi, Kenya Department of Paediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
Mike EnglishKenya Medical Research Institute/Wellcome Trust Research Programme, Nairobi, Kenya Nuffield Department of Medicine, Oxford University, UK.
Clinical Information Network authors
Kenya Medical Research Institute · KEKenya Psychiatry Association​ · KEMinistry of Health · KEUniversity of Nairobi · KEUniversity of Oxford · GB

Funding

Wellcome Trust 092654Wellcome Trust 097170
6 · The paper itself

Abstract

backgroundLack of detailed information about hospital activities, processes and outcomes hampers planning, performance monitoring and improvement in low-income countries (LIC). Clinical networks offer one means to advance methods for data collection and use, informing wider health system development in time, but are rare in LIC. We report baseline data from a new Clinical Information Network (CIN) in Kenya seeking to promote data-informed improvement and learning.

methodsData from 13 hospitals engaged in the Kenyan CIN between April 2014 and March 2015 were captured from medical and laboratory records. We use these data to characterise clinical care and outcomes of hospital admission.

resultsData were available for a total of 30 042 children aged between 2 months and 15 years. Malaria (in five hospitals), pneumonia and diarrhoea/dehydration (all hospitals) accounted for the majority of diagnoses and comorbidity was found in 17 710 (59%) patients. Overall, 1808 deaths (6%) occurred (range per hospital 2.5%-11.1%) with 1037 deaths (57.4%) occurring by day 2 of admission (range 41%-67.8%). While malaria investigations are commonly done, clinical health workers rarely investigate for other possible causes of fever, test for blood glucose in severe illness or ascertain HIV status of admissions. Adherence to clinical guideline-recommended treatment for malaria, pneumonia, meningitis and acute severe malnutrition varied widely across hospitals.

conclusionDeveloping clinical networks is feasible with appropriate support. Early data demonstrate that hospital mortality remains high in Kenya, that resources to investigate severe illness are limited, that care provided and outcomes vary widely and that adoption of effective interventions remains slow. Findings suggest considerable scope for improving care within and across sites.

Indexed as

Hospital MortalityInformation ServicesAdolescentChildChild, PreschoolDiarrheaFemaleHospitalizationHumansInfantKenyaMalariaMaleMalnutritionMeningitisPatient AdmissionEpidemiologyHealth services researchMortalityPaediatric PracticeTropical Paediatrics

Identifiers

PMID26662925
PMCPMC4789757
OpenAlexW2196983317

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.