Evidence map›Paper›PMID 26662468›Full record

ArticleJapanese journal of radiology2016

Safe use of iodinated and gadolinium-based contrast media in current practice in Japan: a questionnaire survey.

Yoshito Tsushima, Tsuneo Ishiguchi, Takamichi Murakami, Hiromitsu Hayashi, Katsumi Hayakawa, Kunihiko Fukuda, Yukunori Korogi, Hideharu Sugimoto, Yasuo Takehara, Yoshifumi Narumi and 6 more

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Article in Japanese journal of radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Diagnostic value of the inner ear computed tomography measurements in detecting congenital sensorineural hearing loss: a comparative study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Article
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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yoshito TsushimaDepartment of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma, 373-8511, Japan. tsushima.rad.gunma@gmail.com.
Tsuneo IshiguchiDepartment of Radiology, Aichi Medical University, Nagakute, Aichi, Japan.
Takamichi MurakamiDepartment of Radiology, Kinki University, Faculty of Medicine, Osaka, Japan.
Hiromitsu HayashiDepartment of Radiology, Nippon Medical School, Tokyo, Japan.
Katsumi HayakawaDepartment of Radiology, Iwate Prefectural Kamaishi Hospital, Kamaishi, Iwate, Japan.
Kunihiko FukudaDepartment of Radiology, The Jikei University School of Medicine, Tokyo, Japan.
Yukunori KorogiDepartment of Radiology, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan.
Hideharu SugimotoDepartment of Radiology, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Yasuo TakeharaDepartment of Radiology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Yoshifumi NarumiDepartment of Radiology, Osaka Medical College, Takatsuki, Osaka, Japan.
Yasuaki AraiDepartment of Diagnostic Radiology, National Cancer Center Hospital, Tokyo, Japan.
Ryohei KuwatsuruDepartment of Radiology, Faculty of Medicine, Juntendo University, Tokyo, Japan.
Kengo YoshimitsuDepartment of Radiology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Kazuo AwaiDepartment of Diagnostic Radiology, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Masayuki KanematsuDepartment of Radiology, Gifu University School of Medicine, Gifu, Gifu, Japan.
Ryo TakagiDepartment of Radiology, Nippon Medical School, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo help establish consensus on the safe use of contrast media in Japan. MATERIALS AND

methodsQuestionnaires were sent to accredited teaching hospitals with radiology residency programs.

resultsThe reply rate was 45.4% (329/724). For contrast-induced nephropathy (CIN), chronic and acute kidney diseases were considered a risk factor in 96.7 and 93.6%, respectively, and dehydration in 73.9%. As preventive actions, intravenous hydration (89.1%) and reduction of iodinated contrast media dose (86.9%) were commonly performed. For nephrogenic systemic fibrosis (NSF), chronic and acute kidney diseases were considered risk factors in 98.5 and 90.6%, respectively, but use of unstable gadolinium-based contrast media was considered a risk factor in only 55.6%. A renal function test was always (63.5% in iodinated; 65.7% in gadolinium) or almost always (23.1; 19.8%) performed, and estimated glomerular filtration rate (eGFR) was the parameter most frequently used (80.8; 82.6%). For the patients with risk factors for acute adverse reaction (AAR), steroid premedication or/and change of contrast medium were frequent preventive actions, but intravenous steroid administration immediately before contrast media use was still performed.

conclusionOur questionnaire survey revealed that preventive actions against CIN were properly performed based on patients' eGFR. Preventive actions against NSF and AAR still lacked consensus.

Indexed as

Breast FeedingContrast MediaFemaleGadoliniumHumansIodineJapanKidney DiseasesKidney Function TestsMaleNephrogenic Fibrosing DermopathyPractice Guidelines as TopicPregnancyRisk FactorsSurveys and QuestionnairesContrast MediaGadoliniumIodineContrast mediumGuidelineJapanQuestionnaireSafety

Identifiers

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Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.