SynthesisPediatric surgery international2016
Laparoscopic versus open splenectomy in children: a systematic review and meta-analysis.
Synthesis in Pediatric surgery international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Comparative outcomes of robot-assisted and open appendicovesicostomy in children: a systematic review and meta-analysis.Pediatric surgery international · 2026Pooled it
- Laparoscopic versus open splenectomy in non-traumatic pediatric patients: a systematic review and meta-analysis.Pediatric surgery international · 2025Pooled it
- Guidelines for the performance of minimally invasive splenectomy.Surgical endoscopy · 2021Pooled it
- A systematic review of the quality of conduct and reporting of systematic reviews and meta-analyses in paediatric surgery.PloS one · 2017Pooled it
- Preoperative splenic artery embolization in moderate splenomegaly undergoing elective laparoscopic splenectomy: a randomized controlled trial.Surgical endoscopy · 2025Trial
- Towards cost saving in surgery without compromising safety: stapleless laparoscopic splenectomy in a developing country-a prospective cohort study.BMJ open quality · 2023Trial
- Retrospective investigation of patients undergoing splenectomy: Our 8-year clinical experience in a single center.Northern clinics of Istanbul · 2025Article
- Littoral cell angioma of a huge spleen with peripheral blood pancytopenia in a 14-year-old boy: a case report and review of the literature.Frontiers in pediatrics · 2024Article
- Case report and literature review: Asymptomatic littoral cell angioma in a 3-year-old girl.Frontiers in pediatrics · 2024Article
- Laparoscopic management of benign splenic tumors in children.World journal of pediatric surgery · 2022Article
- The AlexisUpdates in surgery · 2021Article
- Futility of abdominal drain in elective laparoscopic splenectomy.Langenbeck's archives of surgery · 2020Article
- Clinical and laboratory outcomes following total or partial splenectomy in patients with hereditary spherocytosis.Pediatric hematology and oncology · 2019Article
- A Rare Case of Spontaneous Hemorrhage in a Giant Accessory Spleen in a Child.Case reports in pediatrics · 2019Article
- Laparoscopic splenectomy: a new approach.Clinics (Sao Paulo, Brazil) · 2018Article
- Splenic myoid angioendothelioma mimicking metastatic disease in an 8-year-old with Stage IV Wilms' tumour.BMJ case reports · 2018Article
- Management of immune thrombocytopenia: Korean experts recommendation in 2017.Blood research · 2017Review
- [Minimally invasive surgery in childhood].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe conducted a systematic review and meta-analysis to compare the clinical outcomes between laparoscopic splenectomy and the traditional open splenectomy in children.
methodsLiterature searches were conducted to identify studies having compared the laparoscopic splenectomy (LS) and open splenectomy (OS) for children. Parameters such as operative time, blood loss, length of postoperative stay, the removal of accessory spleens and postoperative complications including postoperative high fever, acute chest syndrome (ACS), and ileus were pooled and compared by meta-analysis.
resultsAmong the 922 pediatric participants included in the 10 studies, 508 had received LS and 414 OS. There were shorter length of hospital stays, less blood loss, and longer operative times with the LS approach compared with OS. However, no significant difference was found between LS and OS in the secondary outcome, such as the removal of accessory spleens or postoperative complications including postoperative high fever, ACS, and ileus.
conclusionLS is a feasible, safe, and effective surgical procedure alternative to OS for pediatric patients. Compared with OS, LS has the advantage of shorter hospital stay and less blood loss. Besides, total postoperative complications may be slightly lower in LS. We conclude that LS should be considered an acceptable option for children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.