Evidence map›Paper›PMID 26661660›Full record

Trial reportJournal of bone and mineral metabolism2017

Visfatin is a positive predictor of bone mineral density in young survivors of acute lymphocytic leukemia.

Adriana Aparecida Siviero-Miachon, Angela Maria Spinola-Castro, Maria Lucia de Martino Lee, Antonio Ramos Calixto, Bruno Geloneze, Marise Lazaretti-Castro, Gil Guerra-Junior

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of bone and mineral metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Adriana Aparecida Siviero-MiachonDivision of Pediatric Endocrinology, Department of Pediatrics, Federal University of Sao Paulo-UNIFESP/EPM, 307 Doutor Diogo de Faria Street, Sao Paulo, 04037-000, Brazil.
Angela Maria Spinola-CastroDivision of Pediatric Endocrinology, Department of Pediatrics, Federal University of Sao Paulo-UNIFESP/EPM, 307 Doutor Diogo de Faria Street, Sao Paulo, 04037-000, Brazil. endocrino@angelaspinola.com.br.
Maria Lucia de Martino LeePediatric Oncology Institute-IOP/GRAACC, UNIFESP/EPM, 743 Botucatu Street, Sao Paulo, 04023-062, Brazil.
Antonio Ramos CalixtoLaboratory of Investigation on Metabolism and Diabetes-LIMED, Faculty of Medical Sciences, State University of Campinas-UNICAMP, 420 Carlos Chagas Street, Campinas, 13083-878, Brazil.
Bruno GelonezeLaboratory of Investigation on Metabolism and Diabetes-LIMED, Faculty of Medical Sciences, State University of Campinas-UNICAMP, 420 Carlos Chagas Street, Campinas, 13083-878, Brazil.
Marise Lazaretti-CastroDivision of Endocrinology and Metabolism, Department of Medicine, Federal University of Sao Paulo-UNIFESP/EPM, 910 Pedro de Toledo Street, Sao Paulo, 04039-032, Brazil.
Gil Guerra-JuniorDivision of Pediatric Endocrinology, Department of Pediatrics, Faculty of Medical Sciences, State University of Campinas-UNICAMP, "Zeferino Vaz" University City, 126 Tessalia Vieira de Camargo Street, Campinas, 13083-887, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal de São Paulo · BRSupport group for adolescents and children with cancer · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone mass acquisition may be compromised in survivors of childhood acute lymphocytic leukemia due to various factors, including adiposity. Fat accumulation can affect bone through the direct effect of adipokines or indirectly through the state of chronic inflammation. The aim of this study was to evaluate the effect of body composition and adipokines on bone mass in survivors of acute lymphocytic leukemia. This was a cross-sectional study of 56 survivors aged between 15 and 24 years, 44.6 % of whom received cranial radiotherapy (18-24 Gy), assessed according to body fat, lean mass, and bone mineral density (dual energy X-ray absorptiometry), computed tomography scan-derived abdominal adipose tissue, and adipokines by a multiple regression analysis. Both lumbar spine L

Indexed as

AdiposityBone DensityPrecursor Cell Lymphoblastic Leukemia-LymphomaSurvivorsAdolescentAdultCross-Sectional StudiesCytokinesFemaleHumansLumbar VertebraeMaleNicotinamide PhosphoribosyltransferasePredictive Value of TestsCytokinesNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, humanAdipokinesBody compositionBone densityMetabolic syndrome XPrecursor cell lymphoblastic leukemia–lymphoma/complications

Identifiers

PMID26661660
OpenAlexW2210574464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.